Phosphinic chloride, bis[4-(1,1-dimethylethyl)phenyl]-

Base Information

Chemical Name:Phosphinic chloride, bis[4-(1,1-dimethylethyl)phenyl]-
CAS No.:100165-90-0
Molecular Formula:C₂₀H₂₆ClOP
Molecular Weight:348.853
Hs Code.:
DSSTox Substance ID:DTXSID901209828

Synonyms:Phosphinic chloride, bis[4-(1,1-dimethylethyl)phenyl]-;DTXSID901209828;100165-90-0

Suppliers and Price of Phosphinic chloride, bis[4-(1,1-dimethylethyl)phenyl]-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Phosphinic chloride, bis[4-(1,1-dimethylethyl)phenyl]-

Chemical Property:

XLogP3:6.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:348.1409801
Heavy Atom Count:23
Complexity:392

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C1=CC=C(C=C1)P(=O)(C2=CC=C(C=C2)C(C)(C)C)Cl

Technology Process of Phosphinic chloride, bis[4-(1,1-dimethylethyl)phenyl]-

There total 3 articles about Phosphinic chloride, bis[4-(1,1-dimethylethyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: bis(4-(tert-butyl)phenyl)phosphinic acid

: 100165-90-0
bis(4-(tert-butyl)phenyl)phosphinic chloride

Guidance literature:: With thionyl chloride; In toluene; at 80 ℃; for 3h; Inert atmosphere;
DOI:10.1002/anie.201606637

Reference yield:

: 3972-65-4
1-bromo-4-tert-butylbenzene

: 100165-90-0
bis(4-(tert-butyl)phenyl)phosphinic chloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: magnesium; 1,1-dibromomethane / tetrahydrofuran / 1 h / Reflux; Inert atmosphere

1.2: 0 °C / Reflux

2.1: dihydrogen peroxide; sodium hydroxide / 1 h / 100 °C / Inert atmosphere

3.1: thionyl chloride / toluene / 3 h / 80 °C / Inert atmosphere

With thionyl chloride; dihydrogen peroxide; magnesium; sodium hydroxide; 1,1-dibromomethane; In tetrahydrofuran; toluene;
DOI:10.1002/anie.201606637

Reference yield:

: 326921-37-3
4,4’-di-tert-butyldiphenylphosphine oxide

: 100165-90-0
bis(4-(tert-butyl)phenyl)phosphinic chloride

Guidance literature:: Multi-step reaction with 2 steps

1: dihydrogen peroxide; sodium hydroxide / 1 h / 100 °C / Inert atmosphere

2: thionyl chloride / toluene / 3 h / 80 °C / Inert atmosphere

With thionyl chloride; dihydrogen peroxide; sodium hydroxide; In toluene;
DOI:10.1002/anie.201606637