2-[4-(dimethylamino)phenyl]-4-oxo-4-p-tolylbutanenitrile

Base Information

• Chemical Name: 2-[4-(dimethylamino)phenyl]-4-oxo-4-p-tolylbutanenitrile
• CAS No.: 1616890-19-7
• Molecular Formula: C₁₉H₂₀N₂O
• Molecular Weight: 292.381
• Mol file: 1616890-19-7.mol

Synonyms:2-[4-(dimethylamino)phenyl]-4-oxo-4-p-tolylbutanenitrile

Chemical Property of 2-[4-(dimethylamino)phenyl]-4-oxo-4-p-tolylbutanenitrile

Chemical Property:

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Technology Process of 2-[4-(dimethylamino)phenyl]-4-oxo-4-p-tolylbutanenitrile

There total 1 articles about 2-[4-(dimethylamino)phenyl]-4-oxo-4-p-tolylbutanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

3-[4-(dimethylamino)phenyl]-1-(4-methylphenyl)prop-2-en-1-one (19132-98-0) + malononitrile (109-77-3) → 2-[4-(dimethylamino)phenyl]-4-oxo-4-p-tolylbutanenitrile (1616890-19-7)

Guidance literature:

With potassium fluoride on basic alumina; In N,N-dimethyl-formamide; at 90 - 100 ℃; for 4h; Green chemistry;

DOI:10.1039/c4gc00386a

upstream raw materials:

3-[4-(dimethylamino)phenyl]-1-(4-methylphenyl)prop-2-en-1-one

malononitrile

Refernces