cis-4-[4-({2-[(1-benzofuran-5-ylcarbonyl)amino]ethyl}carbamoyl)phenoxy]cyclohexanecarboxylic acid

Base Information

Chemical Name:cis-4-[4-({2-[(1-benzofuran-5-ylcarbonyl)amino]ethyl}carbamoyl)phenoxy]cyclohexanecarboxylic acid
CAS No.:1252878-11-7
Molecular Formula:C₂₅H₂₆N₂O₆
Molecular Weight:450.491
Hs Code.:

Synonyms:cis-4-[4-({2-[(1-benzofuran-5-ylcarbonyl)amino]ethyl}carbamoyl)phenoxy]cyclohexanecarboxylic acid

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Chemical Property of cis-4-[4-({2-[(1-benzofuran-5-ylcarbonyl)amino]ethyl}carbamoyl)phenoxy]cyclohexanecarboxylic acid

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Technology Process of cis-4-[4-({2-[(1-benzofuran-5-ylcarbonyl)amino]ethyl}carbamoyl)phenoxy]cyclohexanecarboxylic acid

There total 2 articles about cis-4-[4-({2-[(1-benzofuran-5-ylcarbonyl)amino]ethyl}carbamoyl)phenoxy]cyclohexanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₇H₃₀N₂O₆

: 1252878-11-7
cis-4-[4-({2-[(1-benzofuran-5-ylcarbonyl)amino]ethyl}carbamoyl)phenoxy]cyclohexanecarboxylic acid

Guidance literature:: C₂₇H₃₀N₂O₆; With water; benzotriazol-1-ol; sodium hydroxide; In tetrahydrofuran; ethanol; at 20 ℃;

With hydrogenchloride; In tetrahydrofuran; ethanol; water;

Reference yield:

: 90721-27-0
benzofuran-5-carboxylic acid

: 1252899-09-4
ethyl 4-{4-[(2-aminoethyl)carbamoyl]phenoxy}cyclohexanecarboxylate hydrochloride

: 1252878-11-7
cis-4-[4-({2-[(1-benzofuran-5-ylcarbonyl)amino]ethyl}carbamoyl)phenoxy]cyclohexanecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 6 h / 20 °C

2: benzotriazol-1-ol; sodium hydroxide; water / ethanol; tetrahydrofuran / 20 °C

With water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; sodium hydroxide; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide;