D-(-)-threo-1-(p-nitrophenyl)-2-(N-tritylglycylamido)-1,3-propanediol

Base Information

• Chemical Name: D-(-)-threo-1-(p-nitrophenyl)-2-(N-tritylglycylamido)-1,3-propanediol
• CAS No.: 151371-10-7
• Molecular Formula: C₃₀H₂₉N₃O₅
• Molecular Weight: 511.577
• Mol file: 151371-10-7.mol

Synonyms:D-(-)-threo-1-(p-nitrophenyl)-2-(N-tritylglycylamido)-1,3-propanediol

Chemical Property of D-(-)-threo-1-(p-nitrophenyl)-2-(N-tritylglycylamido)-1,3-propanediol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of D-(-)-threo-1-(p-nitrophenyl)-2-(N-tritylglycylamido)-1,3-propanediol

There total 1 articles about D-(-)-threo-1-(p-nitrophenyl)-2-(N-tritylglycylamido)-1,3-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

tritylglycine N-hydroxysuccimide ester (3397-28-2) + (1R,2R)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol (119-62-0,716-61-0,2792-51-0,2792-52-1,2964-48-9,3689-55-2,63526-31-8,71115-69-0,140694-64-0) → D-(-)-threo-1-(p-nitrophenyl)-2-(N-tritylglycylamido)-1,3-propanediol (151371-10-7)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 3.33333h;

DOI:10.1021/jm00075a008

Reference yield: 83.0%

toluene-4-sulfonic acid (104-15-4) + D-(-)-threo-1-(p-nitrophenyl)-2-(N-tritylglycylamido)-1,3-propanediol (151371-10-7) → 2-Amino-N-[(1R,2R)-2-hydroxy-1-hydroxymethyl-2-(4-nitro-phenyl)-ethyl]-acetamide; compound with toluene-4-sulfonic acid

Guidance literature:

In isopropyl alcohol; at 60 ℃; for 0.333333h;

DOI:10.1021/jm00075a008

Reference yield:

D-(-)-threo-1-(p-nitrophenyl)-2-(N-tritylglycylamido)-1,3-propanediol (151371-10-7) → D-(-)-threo-1-(p-nitrophenyl)-2-(glycylamido)-1,3-propanediol (13215-27-5)

Guidance literature:

With acetic acid; at 60 ℃; for 0.333333h;

DOI:10.1021/jm00075a008

upstream raw materials:

tritylglycine N-hydroxysuccimide ester

(1R,2R)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol

Downstream raw materials:

D-(-)-threo-1-(p-nitrophenyl)-2-(glycylamido)-1,3-propanediol