5-Pyrimidinemethanamine, alpha-methyl- (9CI)

Base Information

• Chemical Name: 5-Pyrimidinemethanamine, alpha-methyl- (9CI)
• CAS No.: 179323-61-6
• Molecular Formula: C₆H₉N₃
• Molecular Weight: 123.158
• Hs Code.: 2933599090
• Mol file: 179323-61-6.mol

Synonyms:5-(1-Aminoethyl)pyrimidine;

Chemical Property of 5-Pyrimidinemethanamine, alpha-methyl- (9CI)

Chemical Property:

• Vapor Pressure: 0.114mmHg at 25°C
• Refractive Index: 1.54
• Boiling Point: 220.357 °C at 760 mmHg
• Flash Point: 109.532 °C
• PSA: 51.80000
• Density: 1.089 g/cm³
• LogP: 1.19660

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-(1-Aminoethyl)pyrimidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-(1-Aminoethyl)pyrimidine was used as in intermediate in the synthesis of benzimidazolone muscarinic antagonists.

Technology Process of 5-Pyrimidinemethanamine, alpha-methyl- (9CI)

There total 2 articles about 5-Pyrimidinemethanamine, alpha-methyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-methyl-N-[1-(pyrimidin-5-yl)ethyl]propane-2-sulfinamide → 1-(5-pyrimidin-yl)ethanamine (179323-61-6,179601-39-9)

Guidance literature:

With hydrogenchloride; In methanol; water; at 15 ℃; for 1h;

DOI:10.1021/acs.jmedchem.1c01849

Reference yield:

→ 1-(5-pyrimidin-yl)ethanamine (179323-61-6,179601-39-9)

Guidance literature:

Azid IV (R = N3), H2/PtO2;

Refernces