C₂₀⁽¹³⁾CH₂₄⁽²⁾H₃N₃O₄S

Base Information

• Chemical Name: C₂₀⁽¹³⁾CH₂₄⁽²⁾H₃N₃O₄S
• CAS No.: 1028386-95-9
• Molecular Formula: C₂₁H₂₇N₃O₄S
• Molecular Weight: 421.494
• Mol file: 1028386-95-9.mol

Synonyms:C₂₀⁽¹³⁾CH₂₄⁽²⁾H₃N₃O₄S

Chemical Property of C₂₀⁽¹³⁾CH₂₄⁽²⁾H₃N₃O₄S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₂₀⁽¹³⁾CH₂₄⁽²⁾H₃N₃O₄S

There total 6 articles about C₂₀⁽¹³⁾CH₂₄⁽²⁾H₃N₃O₄S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C7(13)CH10(2)H3ClO2S (1028386-93-7) + 4-(2-diazolyl)-L-phenylalanine methyl ester (762237-81-0) → C20(13)CH24(2)H3N3O4S (1028386-95-9)

Guidance literature:

With potassium carbonate; In dichloromethane;

DOI:10.1002/jlcr.1223

Reference yield:

C5(13)CH9(2)H3O3 (1028386-91-5) → C20(13)CH24(2)H3N3O4S (1028386-95-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / DIAD; PPh₃ / tetrahydrofuran / 2 h / 20 °C

2: 100 percent / thionyl chloride / CH₂Cl₂ / 20 °C

3: 90 percent / K₂CO₃ / CH₂Cl₂

With thionyl chloride; di-isopropyl azodicarboxylate; potassium carbonate; triphenylphosphine; In tetrahydrofuran; dichloromethane; 1: Mitsunobu reaction;

DOI:10.1002/jlcr.1223

Reference yield:

C14(13)CH16(2)H3NO3 (1028386-89-1) → C20(13)CH24(2)H3N3O4S (1028386-95-9)

Guidance literature:

Multi-step reaction with 5 steps

1.1: LiOH; H₂O₂ / tetrahydrofuran; H₂O / 20 °C

1.2: Na₂SO₃ / 0 - 5 °C

1.3: 88 percent / LiOH / H₂O / 65 °C

2.1: 92 percent / DIAD; PPh₃ / tetrahydrofuran / 2 h / 20 °C

3.1: 100 percent / thionyl chloride / CH₂Cl₂ / 20 °C

4.1: 90 percent / K₂CO₃ / CH₂Cl₂

With lithium hydroxide; thionyl chloride; di-isopropyl azodicarboxylate; dihydrogen peroxide; potassium carbonate; triphenylphosphine; In tetrahydrofuran; dichloromethane; water; 3.1: Mitsunobu reaction;

DOI:10.1002/jlcr.1223

upstream raw materials:

C₇⁽¹³⁾CH₁₀⁽²⁾H₃ClO₂S

4-(2-diazolyl)-L-phenylalanine methyl ester

C₁₄⁽¹³⁾CH₁₆⁽²⁾H₃NO₃

C₁₅⁽¹³⁾CH₁₈⁽²⁾H₃NO₄