C₂₀H₂₂F₂N₂O₂

Base Information

Chemical Name:C₂₀H₂₂F₂N₂O₂
CAS No.:1594127-82-8
Molecular Formula:C₂₀H₂₂F₂N₂O₂
Molecular Weight:360.404
Hs Code.:

C<sub>20</sub>H<sub>22</sub>F<sub>2</sub>N<sub>2</sub>O<sub>2</sub>

Synonyms:C₂₀H₂₂F₂N₂O₂

Suppliers and Price of C₂₀H₂₂F₂N₂O₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₀H₂₂F₂N₂O₂

Chemical Property:

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Technology Process of C₂₀H₂₂F₂N₂O₂

There total 7 articles about C₂₀H₂₂F₂N₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 348-61-8
1-bromo-3,4-difluorobenzene

: 1594129-68-6
N-((S)-1-(4-((R)-pyrrolidin-3-yloxy)phenyl)ethyl)acetamide hydrochloride

: 1594127-82-8
C₂₀H₂₂F₂N₂O₂

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; johnphos; sodium t-butanolate; In 1,4-dioxane; at 80 ℃; Inert atmosphere;

Reference yield:

: 1443670-29-8
(S)-N-(1-(4-hydroxyphenyl)ethyl)acetamide

: 1594127-82-8
C₂₀H₂₂F₂N₂O₂

Guidance literature:: Multi-step reaction with 3 steps

1: caesium carbonate / N,N-dimethyl-formamide / 80 °C

2: hydrogenchloride / 1,4-dioxane / 20 °C

3: sodium t-butanolate; johnphos; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane / 80 °C / Inert atmosphere

With hydrogenchloride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; johnphos; sodium t-butanolate; In 1,4-dioxane; N,N-dimethyl-formamide; 3: |Buchwald-Hartwig Coupling;

Reference yield:

: (S)-N-(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)acetamide

: 1594127-82-8
C₂₀H₂₂F₂N₂O₂

Guidance literature:: Multi-step reaction with 4 steps

1: dihydrogen peroxide; sodium hydroxide / water; tetrahydrofuran / 2 h / 0 °C

2: caesium carbonate / N,N-dimethyl-formamide / 80 °C

3: hydrogenchloride / 1,4-dioxane / 20 °C

4: sodium t-butanolate; johnphos; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane / 80 °C / Inert atmosphere

With hydrogenchloride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; dihydrogen peroxide; caesium carbonate; sodium hydroxide; johnphos; sodium t-butanolate; In tetrahydrofuran; 1,4-dioxane; water; N,N-dimethyl-formamide; 4: |Buchwald-Hartwig Coupling;