4-Hydroxy-2-(phenylamino)pyrimidine-5-carboxylic acid

Base Information

Chemical Name:4-Hydroxy-2-(phenylamino)pyrimidine-5-carboxylic acid
CAS No.:124769-60-4
Molecular Formula:C₁₁H₉N₃O₃
Molecular Weight:231.211
Hs Code.:
ChEMBL ID:CHEMBL4559385
DSSTox Substance ID:DTXSID60603475
Wikidata:Q82500895
Mol file:124769-60-4.mol

Synonyms:4-Hydroxy-2-(phenylamino)pyrimidine-5-carboxylic acid;124769-60-4;2-anilino-6-oxo-1H-pyrimidine-5-carboxylic acid;4-Hydroxy-2-(phenylamino)pyrimidine-5-carboxylicacid;CHEMBL4559385;SCHEMBL10745912;DTXSID60603475;SB59305;AM807582;DB-332314;A890358;2-Anilino-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid

Suppliers and Price of 4-Hydroxy-2-(phenylamino)pyrimidine-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-Hydroxy-2-(phenylamino)pyrimidine-5-carboxylic acid 95%
10g
$ 7216.00

Matrix Scientific
4-Hydroxy-2-(phenylamino)pyrimidine-5-carboxylic acid 95%
5g
$ 5541.00

Chemenu
4-Hydroxy-2-(phenylamino)pyrimidine-5-carboxylicacid 95%
1g
$ 1365.00

American Custom Chemicals Corporation
4-HYDROXY-2-(PHENYLAMINO)PYRIMIDINE-5-CARBOXYLIC ACID 95.00%
5MG
$ 505.13

AK Scientific
4-Hydroxy-2-(phenylamino)pyrimidine-5-carboxylicacid
5g
$ 7530.00

Total 6 raw suppliers

Chemical Property of 4-Hydroxy-2-(phenylamino)pyrimidine-5-carboxylic acid

Chemical Property:

Storage Temp.:2-8°C
XLogP3:0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:231.06439116
Heavy Atom Count:17
Complexity:395

Purity/Quality:

97% ^*data from raw suppliers

4-Hydroxy-2-(phenylamino)pyrimidine-5-carboxylic acid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC2=NC=C(C(=O)N2)C(=O)O

Technology Process of 4-Hydroxy-2-(phenylamino)pyrimidine-5-carboxylic acid

There total 3 articles about 4-Hydroxy-2-(phenylamino)pyrimidine-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 98772-43-1
ethyl 6-oxo-2-(phenylamino)-1,6-diydropyrimidine-5-carboxylate

: 124769-60-4
6-oxo-2-(phenylamino)-1,6-diydropyrimidine-5-carboxylic acid

Guidance literature:: With sodium hydroxide; In methanol; at 80 ℃; for 2h;
DOI:10.1248/cpb.37.1780

Reference yield:

: 53554-29-3
ethyl 3,4-dihydro-2-methylthio-4-oxopyrimidine-5-carboxylate

: 124769-60-4
6-oxo-2-(phenylamino)-1,6-diydropyrimidine-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 2 h / 160 °C / Reflux

2: water; sodium hydroxide / methanol / 40 - 80 °C

With water; sodium hydroxide; In methanol; ethanol;

Reference yield:

: sodium 5-(ethoxycarbonyl)-2-(methylthio)-4-oxo-4H-pyrimidin-3-ide

: 124769-60-4
6-oxo-2-(phenylamino)-1,6-diydropyrimidine-5-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / water; methanol

2: ethanol / 2 h / 160 °C / Reflux

3: water; sodium hydroxide / methanol / 40 - 80 °C

With hydrogenchloride; water; sodium hydroxide; In methanol; ethanol; water;