3-(6-cyclopropanesulfonylpyridin-3-yloxy)-5-((S)-2-methoxy-1-methylethoxy)benzoic acid

Base Information

Chemical Name:3-(6-cyclopropanesulfonylpyridin-3-yloxy)-5-((S)-2-methoxy-1-methylethoxy)benzoic acid
CAS No.:1325708-46-0
Molecular Formula:C₁₉H₂₁NO₇S
Molecular Weight:407.444
Hs Code.:

Synonyms:3-(6-cyclopropanesulfonylpyridin-3-yloxy)-5-((S)-2-methoxy-1-methylethoxy)benzoic acid

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Chemical Property of 3-(6-cyclopropanesulfonylpyridin-3-yloxy)-5-((S)-2-methoxy-1-methylethoxy)benzoic acid

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Technology Process of 3-(6-cyclopropanesulfonylpyridin-3-yloxy)-5-((S)-2-methoxy-1-methylethoxy)benzoic acid

There total 8 articles about 3-(6-cyclopropanesulfonylpyridin-3-yloxy)-5-((S)-2-methoxy-1-methylethoxy)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1325708-43-7
3-(6-cyclopropanesulfonylpyridin-3-yloxy)-5-((S)-2-methoxy-1-methylethoxy)benzoic acid methyl ester

: 1325708-46-0
3-(6-cyclopropanesulfonylpyridin-3-yloxy)-5-((S)-2-methoxy-1-methylethoxy)benzoic acid

Guidance literature:: With lithium hydroxide monohydrate; water; In tetrahydrofuran; methanol; at 20 ℃;

Reference yield:

: 851885-42-2
methyl 3-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}-5-[(phenylmethyl)oxy]benzoate

: 1325708-46-0
3-(6-cyclopropanesulfonylpyridin-3-yloxy)-5-((S)-2-methoxy-1-methylethoxy)benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen / palladium 10% on activated carbon / ethanol; tetrahydrofuran / 20 °C

2: caesium carbonate / ISOPROPYLAMIDE / 8 h / 100 °C

3: water; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 20 °C

With lithium hydroxide monohydrate; water; hydrogen; caesium carbonate; palladium 10% on activated carbon; In tetrahydrofuran; methanol; ethanol; ISOPROPYLAMIDE;

Reference yield:

: 54915-31-0
methyl 3-(benzyloxy)-5-hydroxybenzoate

: 1325708-46-0
3-(6-cyclopropanesulfonylpyridin-3-yloxy)-5-((S)-2-methoxy-1-methylethoxy)benzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 0 - 20 °C

2: hydrogen / palladium 10% on activated carbon / ethanol; tetrahydrofuran / 20 °C

3: caesium carbonate / ISOPROPYLAMIDE / 8 h / 100 °C

4: water; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 20 °C

With lithium hydroxide monohydrate; di-isopropyl azodicarboxylate; water; hydrogen; caesium carbonate; triphenylphosphine; palladium 10% on activated carbon; In tetrahydrofuran; methanol; ethanol; ISOPROPYLAMIDE;