Technology Process of 4-(3-(2-(benzylsulfanyl)-1H-imidazol-4-yl)phenyl)-1-hexyl-3,4-dimethylpiperidine
There total 4 articles about 4-(3-(2-(benzylsulfanyl)-1H-imidazol-4-yl)phenyl)-1-hexyl-3,4-dimethylpiperidine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydrogencarbonate;
In
tetrahydrofuran; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: triethylamine / palladium diacetate / N,N-dimethyl-formamide
2: chloro-trimethyl-silane; bromine; lithium hexamethyldisilazane / tetrahydrofuran
3: potassium carbonate / diethyl ether; water; N,N-dimethyl-formamide
4: sodium hydrogencarbonate / tetrahydrofuran; ethyl acetate
With
chloro-trimethyl-silane; bromine; sodium hydrogencarbonate; potassium carbonate; triethylamine; lithium hexamethyldisilazane;
palladium diacetate;
In
tetrahydrofuran; diethyl ether; water; ethyl acetate; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium carbonate / diethyl ether; water; N,N-dimethyl-formamide
2: sodium hydrogencarbonate / tetrahydrofuran; ethyl acetate
With
sodium hydrogencarbonate; potassium carbonate;
In
tetrahydrofuran; diethyl ether; water; ethyl acetate; N,N-dimethyl-formamide;