(2'R,3'S,6'S,8'R,10'R)-(E)-(+)-4-(10'diphenyl-t-butylsiloxy-2',3'-dimethyl-1',7'-dioxaspiro<5.5>undecan-8'-yl)-2-methylbut-2-enol

Base Information

Chemical Name:(2'R,3'S,6'S,8'R,10'R)-(E)-(+)-4-(10'diphenyl-t-butylsiloxy-2',3'-dimethyl-1',7'-dioxaspiro<5.5>undecan-8'-yl)-2-methylbut-2-enol
CAS No.:107692-08-0
Molecular Formula:C₃₂H₄₆O₄Si
Molecular Weight:522.8
Hs Code.:

Synonyms:(2'R,3'S,6'S,8'R,10'R)-(E)-(+)-4-(10'diphenyl-t-butylsiloxy-2',3'-dimethyl-1',7'-dioxaspiro<5.5>undecan-8'-yl)-2-methylbut-2-enol

Suppliers and Price of (2'R,3'S,6'S,8'R,10'R)-(E)-(+)-4-(10'diphenyl-t-butylsiloxy-2',3'-dimethyl-1',7'-dioxaspiro<5.5>undecan-8'-yl)-2-methylbut-2-enol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2'R,3'S,6'S,8'R,10'R)-(E)-(+)-4-(10'diphenyl-t-butylsiloxy-2',3'-dimethyl-1',7'-dioxaspiro<5.5>undecan-8'-yl)-2-methylbut-2-enol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2'R,3'S,6'S,8'R,10'R)-(E)-(+)-4-(10'diphenyl-t-butylsiloxy-2',3'-dimethyl-1',7'-dioxaspiro<5.5>undecan-8'-yl)-2-methylbut-2-enol

There total 20 articles about (2'R,3'S,6'S,8'R,10'R)-(E)-(+)-4-(10'diphenyl-t-butylsiloxy-2',3'-dimethyl-1',7'-dioxaspiro<5.5>undecan-8'-yl)-2-methylbut-2-enol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 107692-07-9
(2'R,3'S,6'S,8'S,10'R)-(E)-(+)-ethyl 4-(10'diphenyl-t-butylsiloxy-2',3'-dimethyl-1',7'-dioxaspiro<5.5>undecane-8'-yl)-2-methylbut-2-enoate

: 107692-08-0
(2'R,3'S,6'S,8'R,10'R)-(E)-(+)-4-(10'diphenyl-t-butylsiloxy-2',3'-dimethyl-1',7'-dioxaspiro<5.5>undecan-8'-yl)-2-methylbut-2-enol

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane;
DOI:10.1016/S0040-4039(00)84716-4

Reference yield:

: 104705-91-1,107794-79-6
[(2S,4S,6R,8R,9S)-4-(tert-Butyl-diphenyl-silanyloxy)-8,9-dimethyl-1,7-dioxa-spiro[5.5]undec-2-yl]-acetaldehyde

: 107692-08-0
(2'R,3'S,6'S,8'R,10'R)-(E)-(+)-4-(10'diphenyl-t-butylsiloxy-2',3'-dimethyl-1',7'-dioxaspiro<5.5>undecan-8'-yl)-2-methylbut-2-enol

Guidance literature:: Multi-step reaction with 2 steps

1: CH₂Cl₂ / 5 h / Heating

2: Dibal-H / diethyl ether / 1 h / -78 °C

With diisobutylaluminium hydride; In diethyl ether; dichloromethane;
DOI:10.1021/jo00238a031

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 107692-08-0
(2'R,3'S,6'S,8'R,10'R)-(E)-(+)-4-(10'diphenyl-t-butylsiloxy-2',3'-dimethyl-1',7'-dioxaspiro<5.5>undecan-8'-yl)-2-methylbut-2-enol

Guidance literature:: Multi-step reaction with 5 steps

1: 97 percent / DMAP, imidazole / dimethylformamide / 48 h

2: 1.) 9-BBN, 2.) NaOH, 30percent aq. H₂O₂ / 1.) THF, irradiation, 1 h, 2.) 4 h

3: 1.) oxalyl chloride, DMSO, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 15 min, 2.) -78 deg C, 5 min

4: CH₂Cl₂ / 5 h / Heating

5: Dibal-H / diethyl ether / 1 h / -78 °C

With 1H-imidazole; dmap; sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; oxalyl dichloride; dihydrogen peroxide; diisobutylaluminium hydride; dimethyl sulfoxide; triethylamine; In diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo00238a031