Technology Process of 2,3',6-trihydroxy-4-<1-(carbo-tert-butoxy)-3,4-dihydroxybutoxy>-4'-propoxydihydrochalcone
There total 11 articles about 2,3',6-trihydroxy-4-<1-(carbo-tert-butoxy)-3,4-dihydroxybutoxy>-4'-propoxydihydrochalcone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
dichloromethane; tert-butyl alcohol;
for 4h;
under 2280 Torr;
Ambient temperature;
DOI:10.1021/jm00136a011
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 64 percent / 10percent aq. KOH / 4 h / Heating
2: 48.1 g / K2CO3 / dimethylformamide / 1.) RT, 21 h, 2.) 80 deg C, 6 h
3: 3.80 g / 3percent aq. H2SO4 / ethanol / 22 h
4: 76 percent / 60percent aq. KOH / ethanol / 72 h / Ambient temperature
5: 89 percent / K2CO3 / dimethylformamide / 48 h / Ambient temperature
6: 60 percent / aq. H2SO4 / dioxane / 30 h / Ambient temperature
7: 63 percent / H2 / Pd/C / 2-methyl-propan-2-ol; CH2Cl2 / 4 h / 2280 Torr / Ambient temperature
With
potassium hydroxide; sulfuric acid; hydrogen; potassium carbonate;
palladium on activated charcoal;
In
1,4-dioxane; ethanol; dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1021/jm00136a011
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 59 percent / m-chloroperbenzoic acid / CH2Cl2 / 14 h / Ambient temperature
2: 89 percent / K2CO3 / dimethylformamide / 48 h / Ambient temperature
3: 60 percent / aq. H2SO4 / dioxane / 30 h / Ambient temperature
4: 63 percent / H2 / Pd/C / 2-methyl-propan-2-ol; CH2Cl2 / 4 h / 2280 Torr / Ambient temperature
With
sulfuric acid; hydrogen; potassium carbonate; 3-chloro-benzenecarboperoxoic acid;
palladium on activated charcoal;
In
1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1021/jm00136a011
