N-(4-fluorobenzyl)matrinic acid

Base Information

• Chemical Name: N-(4-fluorobenzyl)matrinic acid
• CAS No.: 1345730-84-8
• Molecular Formula: C₂₂H₃₁FN₂O₂
• Molecular Weight: 374.499
• Mol file: 1345730-84-8.mol

Synonyms:N-(4-fluorobenzyl)matrinic acid

Chemical Property of N-(4-fluorobenzyl)matrinic acid

Chemical Property:

Purity/Quality:

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Technology Process of N-(4-fluorobenzyl)matrinic acid

There total 7 articles about N-(4-fluorobenzyl)matrinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

C23H33FN2O2 → N-(4-fluorobenzyl)matrinic acid (1345730-84-8)

Guidance literature:

With sodium hydroxide; In methanol; Reflux;

DOI:10.1021/acs.jafc.8b04965

Reference yield:

C29H36F2N2O2 → N-(4-fluorobenzyl)matrinic acid (1345730-84-8)

Guidance literature:

With sodium hydroxide; In ethanol; at 85 ℃; for 4h;

DOI:10.1016/j.bmcl.2021.128503

Reference yield:

C35H41FN2O2 → N-(4-fluorobenzyl)matrinic acid (1345730-84-8)

Guidance literature:

With 3-methyl-phenol; at 110 ℃;

upstream raw materials:

(+)-matrine

1-chloromethyl-4-fluorobenzene

C₁₆H₂₈N₂O₂

matrinic acid