N-[(1-(tert-butoxycarbonylamino)-cyclopent-3-enyl)carbonyl]-L-phenylalanine methyl ester

Base Information

Chemical Name:N-[(1-(tert-butoxycarbonylamino)-cyclopent-3-enyl)carbonyl]-L-phenylalanine methyl ester
CAS No.:354526-96-8
Molecular Formula:C₂₁H₂₈N₂O₅
Molecular Weight:388.464
Hs Code.:

Synonyms:N-[(1-(tert-butoxycarbonylamino)-cyclopent-3-enyl)carbonyl]-L-phenylalanine methyl ester

Suppliers and Price of N-[(1-(tert-butoxycarbonylamino)-cyclopent-3-enyl)carbonyl]-L-phenylalanine methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[(1-(tert-butoxycarbonylamino)-cyclopent-3-enyl)carbonyl]-L-phenylalanine methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[(1-(tert-butoxycarbonylamino)-cyclopent-3-enyl)carbonyl]-L-phenylalanine methyl ester

There total 10 articles about N-[(1-(tert-butoxycarbonylamino)-cyclopent-3-enyl)carbonyl]-L-phenylalanine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 7524-50-7
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

: 213316-20-2
1-(tert-butoxycarbonylamino)-3-cyclopentene-1-carboxylic acid

: 354526-96-8
N-[(1-(tert-butoxycarbonylamino)-cyclopent-3-enyl)carbonyl]-L-phenylalanine methyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 60 ℃; for 0.5h; microwave irradiation;
DOI:10.1016/j.tet.2007.06.108

Reference yield: 75.0%

: 354526-85-5
2-(2-allyl-2-tert-butoxycarbonylamino-pent-4-enoylamino)-3-phenyl-propionic acid methyl ester

: 354526-96-8
N-[(1-(tert-butoxycarbonylamino)-cyclopent-3-enyl)carbonyl]-L-phenylalanine methyl ester

Guidance literature:: With Grubbs catalyst first generation; In toluene; for 12h; Heating;
DOI:10.1016/S0960-894X(01)00227-X

Reference yield:

: 952193-55-4
(2R)-5,5-diallyl-3,6-diethoxy-2,5-dihydro-2-isopropylpyrazine

: 354526-96-8
N-[(1-(tert-butoxycarbonylamino)-cyclopent-3-enyl)carbonyl]-L-phenylalanine methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 63 percent / Grubbs second generation catalyst / CH₂Cl₂ / 0.25 h / 140 °C / microwave irradiation

2: TFA; water / acetonitrile / 0.33 h / 60 °C / microwave irradiation

3: 0.56 g / tetrahydrofuran / 20 h / Heating

4: 80 percent / lithium hydroxide / tetrahydrofuran; H₂O / 0.33 h / 60 °C / microwave irradiation

5: 94 percent / HATU; DIPEA / dimethylformamide / 0.5 h / 60 °C / microwave irradiation

With lithium hydroxide; water; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.tet.2007.06.108