(5R,7S)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

Base Information

Chemical Name:(5R,7S)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione
CAS No.:1011732-51-6
Molecular Formula:C₁₄H₁₆FN₃O₂
Molecular Weight:277.298
Hs Code.:

Synonyms:(5R,7S)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (5R,7S)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

Chemical Property:

Purity/Quality:

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Technology Process of (5R,7S)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

There total 1 articles about (5R,7S)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (5R,7S)-1-(3-fluorophenyl)-8-(3-isopropoxybenzyl)-7-methyl-2,4-dioxo-1,3-diaza-8-azoniaspiro[4.5]decane trifluoroacetate

: 1011732-51-6
(5R,7S)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

Guidance literature:: With hydrogen; 20% Pd(OH)2 on carbon; In methanol; for 16h;

Reference yield:

: 1011732-51-6
(5R,7S)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

: 100-44-7
benzyl chloride

: 76-05-1
trifluoroacetic acid

: 1011732-53-8
(5R,7S)-8-benzyl-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

Guidance literature:: (5R,7S)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione; benzyl chloride; With triethylamine; In dimethyl sulfoxide; at 20 ℃; for 16h;

trifluoroacetic acid; Product distribution / selectivity;

Reference yield:

: 1011732-51-6
(5R,7S)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

: 100-44-7
benzyl chloride

: 76-05-1
trifluoroacetic acid

: 338776-97-9
3-(chloromethyl)-5-(3,4-dichlorophenyl)isoxazole

Guidance literature:: (5R,7S)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione; benzyl chloride; With triethylamine; In dimethyl sulfoxide; at 20 ℃; for 16h;

trifluoroacetic acid; Product distribution / selectivity;