Cyclohexane, 2-ethynyl-4-methyl-1-(1-methylethyl)-, (1S,2R,4R)- (9CI)

Base Information

• Chemical Name: Cyclohexane, 2-ethynyl-4-methyl-1-(1-methylethyl)-, (1S,2R,4R)- (9CI)
• CAS No.: 178243-92-0
• Molecular Formula: C₁₂H₂₀
• Molecular Weight: 164.291
• Mol file: 178243-92-0.mol

Synonyms:Cyclohexane,2-ethynyl-4-methyl-1-(1-methylethyl)-, [1S-(1a,2b,4b)]-; (-)-Menthylacetylene

Chemical Property of Cyclohexane, 2-ethynyl-4-methyl-1-(1-methylethyl)-, (1S,2R,4R)- (9CI)

Chemical Property:

• PSA: 0.00000
• LogP: 3.32800

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclohexane, 2-ethynyl-4-methyl-1-(1-methylethyl)-, (1S,2R,4R)- (9CI)

There total 3 articles about Cyclohexane, 2-ethynyl-4-methyl-1-(1-methylethyl)-, (1S,2R,4R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C12H21Br → (1R,2R,4R)-2-ethynyl-1-isopropyl-4-methylcyclohexane (178243-92-0)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -78 - 20 ℃; for 1h;

DOI:10.1002/anie.201600599

Reference yield:

(1S,4R)-1-isopropyl-4-methyl-2-vinylidenecyclohexane → (1S,2R,4R)-2-Ethynyl-1-isopropyl-4-methyl-cyclohexane (178243-92-0) + (1S,2S,4R)-2-Ethynyl-1-isopropyl-4-methyl-cyclohexane (178243-92-0)

Guidance literature:

With potassium N-methylbutylamide; In tetrahydrofuran; at 0 ℃; for 0.25h; Product distribution; other metal amides, temperatures, time; alkali metal amide-mediated isomerization of terminal allenes; diastereoselectivity; isomerization of deuterated and sterically hindered terminal allenes;

DOI:10.1021/jo960276i

Reference yield:

(1S,4R)-1-isopropyl-4-methyl-2-vinylidenecyclohexane → (1S,2R,4R)-2-Ethynyl-1-isopropyl-4-methyl-cyclohexane (178243-92-0) + (1S,2S,4R)-2-Ethynyl-1-isopropyl-4-methyl-cyclohexane (178243-92-0)

Guidance literature:

With potassium N-methylbutylamide; In tetrahydrofuran; at 0 ℃; for 0.25h; Product distribution; other metal amides, temperatures, time; alkali metal amide-mediated isomerization of terminal allenes; diastereoselectivity; isomerization of deuterated and sterically hindered terminal allenes;

DOI:10.1021/jo960276i

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 178243-92-0 Cyclohexane, 2-ethynyl-4-methyl-1-(1-methylethyl)-, (1S,2R,4R)- (9CI)

Send

Send

Metric Ton KG G Pound L ML

Send

Send