methyl 2,6-anhydro-3,4-bis(O-tert-butyldimethylsilyl)-7-O-(4-methoxybenzyl)-D-glycero-L-manno-heptonate

Base Information

Chemical Name:methyl 2,6-anhydro-3,4-bis(O-tert-butyldimethylsilyl)-7-O-(4-methoxybenzyl)-D-glycero-L-manno-heptonate
CAS No.:944072-35-9
Molecular Formula:C₂₈H₅₀O₈Si₂
Molecular Weight:570.871
Hs Code.:

Synonyms:methyl 2,6-anhydro-3,4-bis(O-tert-butyldimethylsilyl)-7-O-(4-methoxybenzyl)-D-glycero-L-manno-heptonate

Suppliers and Price of methyl 2,6-anhydro-3,4-bis(O-tert-butyldimethylsilyl)-7-O-(4-methoxybenzyl)-D-glycero-L-manno-heptonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2,6-anhydro-3,4-bis(O-tert-butyldimethylsilyl)-7-O-(4-methoxybenzyl)-D-glycero-L-manno-heptonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2,6-anhydro-3,4-bis(O-tert-butyldimethylsilyl)-7-O-(4-methoxybenzyl)-D-glycero-L-manno-heptonate

There total 5 articles about methyl 2,6-anhydro-3,4-bis(O-tert-butyldimethylsilyl)-7-O-(4-methoxybenzyl)-D-glycero-L-manno-heptonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: methyl 2,6-anhydro-3,4-bis(O-tert-butyldimethylsilyl)-5,7-O-(4-methoxybenzylidene)-D-glycero-L-manno-heptonate

: 944072-35-9
methyl 2,6-anhydro-3,4-bis(O-tert-butyldimethylsilyl)-7-O-(4-methoxybenzyl)-D-glycero-L-manno-heptonate

Guidance literature:: With 4 Angstroem MS; sodium cyanoborohydride; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; at 20 ℃; for 24h;
DOI:10.1055/s-2007-965942

Reference yield:

: methyl 2,6-anhydro-5,7-O-(4-methoxybenzylidene)-D-glycero-L-manno-heptonate

: 944072-35-9
methyl 2,6-anhydro-3,4-bis(O-tert-butyldimethylsilyl)-7-O-(4-methoxybenzyl)-D-glycero-L-manno-heptonate

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / imidazole; DMAP / dimethylformamide / 24 h / 65 °C

2: 64 percent / sodium cyanoborohydride; 4 Angstroem MS; TFA / tetrahydrofuran; CH₂Cl₂ / 24 h / 20 °C

With 1H-imidazole; dmap; 4 Angstroem MS; sodium cyanoborohydride; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1055/s-2007-965942

Reference yield:

: 57039-37-9
(2R,3R,45,5R,6R)-methyl 3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-carboxylate

: 944072-35-9
methyl 2,6-anhydro-3,4-bis(O-tert-butyldimethylsilyl)-7-O-(4-methoxybenzyl)-D-glycero-L-manno-heptonate

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / TsOH*H₂O / acetonitrile / 1.67 h / 20 °C

2: 80 percent / imidazole; DMAP / dimethylformamide / 24 h / 65 °C

3: 64 percent / sodium cyanoborohydride; 4 Angstroem MS; TFA / tetrahydrofuran; CH₂Cl₂ / 24 h / 20 °C

With 1H-imidazole; dmap; 4 Angstroem MS; sodium cyanoborohydride; toluene-4-sulfonic acid; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1055/s-2007-965942