[4-azido-2-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-butoxymethyl]-phosphonic acid

Base Information

Chemical Name:[4-azido-2-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-butoxymethyl]-phosphonic acid
CAS No.:957139-67-2
Molecular Formula:C₃₀H₃₁N₈O₅P
Molecular Weight:614.601
Hs Code.:

Synonyms:[4-azido-2-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-butoxymethyl]-phosphonic acid

Suppliers and Price of [4-azido-2-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-butoxymethyl]-phosphonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [4-azido-2-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-butoxymethyl]-phosphonic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [4-azido-2-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-butoxymethyl]-phosphonic acid

There total 5 articles about [4-azido-2-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-butoxymethyl]-phosphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 889885-75-0
(+/-)-9-[1-[(diisopropylphosphono)methoxy]methyl][(3-azido)propyl]-N⁶-(4-monomethoxytrityl)-adenine

: 957139-67-2
[4-azido-2-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-butoxymethyl]-phosphonic acid

Guidance literature:: With trimethylsilyl iodide; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 16h;
DOI:10.1080/15257770500265315

Reference yield:

: 889885-74-9
(+/-)-9-[1-[(diisopropylphosphono)methoxy]methyl][(3-hydroxy)-propyl]-N⁶-(4-monomethoxytrityl)-adenine

: 957139-67-2
[4-azido-2-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-butoxymethyl]-phosphonic acid

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 20 h / 20 °C

2: 458 mg / NaN₃ / dimethylformamide / 4 h / 100 °C

3: 44 percent / Et₃N; trimethylsilyl iodide / dimethylformamide / 16 h / 20 °C

With pyridine; sodium azide; trimethylsilyl iodide; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1080/15257770500265315

Reference yield:

: methanesulfonic acid 4-(diisopropoxy-phosphorylmethoxy)-3-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-butyl ester

: 957139-67-2
[4-azido-2-(6-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-purin-9-yl)-butoxymethyl]-phosphonic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 458 mg / NaN₃ / dimethylformamide / 4 h / 100 °C

2: 44 percent / Et₃N; trimethylsilyl iodide / dimethylformamide / 16 h / 20 °C

With sodium azide; trimethylsilyl iodide; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1080/15257770500265315