benzyl (2-ethoxy-1-hydroxy-4-oxo-3-pentyl-2-cyclobutenyl)acetate

Base Information

• Chemical Name: benzyl (2-ethoxy-1-hydroxy-4-oxo-3-pentyl-2-cyclobutenyl)acetate
• CAS No.: 158599-40-7
• Molecular Formula: C₂₀H₂₆O₅
• Molecular Weight: 346.423
• Mol file: 158599-40-7.mol

Synonyms:benzyl (2-ethoxy-1-hydroxy-4-oxo-3-pentyl-2-cyclobutenyl)acetate

Chemical Property of benzyl (2-ethoxy-1-hydroxy-4-oxo-3-pentyl-2-cyclobutenyl)acetate

Chemical Property:

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Technology Process of benzyl (2-ethoxy-1-hydroxy-4-oxo-3-pentyl-2-cyclobutenyl)acetate

There total 1 articles about benzyl (2-ethoxy-1-hydroxy-4-oxo-3-pentyl-2-cyclobutenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

lithium enolate of benzyl acetate + 3-ethoxy-4-pentyl-3-cyclobotene-1,2-dione → benzyl (2-ethoxy-1-hydroxy-4-oxo-3-pentyl-2-cyclobutenyl)acetate (158599-40-7)

Guidance literature:

In tetrahydrofuran; at -78 ℃;

DOI:10.1021/jo00096a001

Reference yield: 55.0%

benzyl (2-ethoxy-1-hydroxy-4-oxo-3-pentyl-2-cyclobutenyl)acetate (158599-40-7) + lead tetraacetate → (Z)-multicolanate + (2-Acetoxy-3-ethoxy-5-oxo-4-pentyl-2,5-dihydro-furan-2-yl)-acetic acid benzyl ester (158622-01-6)

Guidance literature:

In toluene; for 1h;

DOI:10.1021/ja00143a006

Reference yield: 55.0%

lead(IV) tetraacetate (546-67-8) + benzyl (2-ethoxy-1-hydroxy-4-oxo-3-pentyl-2-cyclobutenyl)acetate (158599-40-7) → (Z)-multicolanate + (2-Acetoxy-3-ethoxy-5-oxo-4-pentyl-2,5-dihydro-furan-2-yl)-acetic acid benzyl ester (158622-01-6)

Guidance literature:

In toluene; Ambient temperature;

DOI:10.1021/jo00096a001

Downstream raw materials:

(2-Acetoxy-3-ethoxy-5-oxo-4-pentyl-2,5-dihydro-furan-2-yl)-acetic acid benzyl ester