1-(4-methoxyphenyl)-4-[2-(6-bromoisochroman-1-yl)ethyl]piperazine

Base Information

• Chemical Name: 1-(4-methoxyphenyl)-4-[2-(6-bromoisochroman-1-yl)ethyl]piperazine
• CAS No.: 170858-54-5
• Molecular Formula: C₂₂H₂₇BrN₂O₂
• Molecular Weight: 431.373
• Mol file: 170858-54-5.mol

Synonyms:1-(4-methoxyphenyl)-4-[2-(6-bromoisochroman-1-yl)ethyl]piperazine

Chemical Property of 1-(4-methoxyphenyl)-4-[2-(6-bromoisochroman-1-yl)ethyl]piperazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-methoxyphenyl)-4-[2-(6-bromoisochroman-1-yl)ethyl]piperazine

There total 3 articles about 1-(4-methoxyphenyl)-4-[2-(6-bromoisochroman-1-yl)ethyl]piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(6-Bromo-isochroman-1-yl)-1-[4-(4-methoxy-phenyl)-piperazin-1-yl]-ethanone (187668-54-8) → 1-(4-methoxyphenyl)-4-[2-(6-bromoisochroman-1-yl)ethyl]piperazine (170858-54-5)

Guidance literature:

With borane-THF;

DOI:10.1021/jm980137o

Reference yield:

4-(4-methoxyphenyl)piperazine (38212-30-5) → 1-(4-methoxyphenyl)-4-[2-(6-bromoisochroman-1-yl)ethyl]piperazine (170858-54-5)

Guidance literature:

Multi-step reaction with 2 steps

1: DECP

2: BH₃*THF

With borane-THF; diethyl chlorophosphate;

DOI:10.1021/jm980137o

Reference yield:

(6-bromoisochroman-1-yl)acetic acid (187667-63-6) → 1-(4-methoxyphenyl)-4-[2-(6-bromoisochroman-1-yl)ethyl]piperazine (170858-54-5)

Guidance literature:

Multi-step reaction with 2 steps

1: DECP

2: BH₃*THF

With borane-THF; diethyl chlorophosphate;

DOI:10.1021/jm980137o

upstream raw materials:

2-(6-Bromo-isochroman-1-yl)-1-[4-(4-methoxy-phenyl)-piperazin-1-yl]-ethanone

4-(4-methoxyphenyl)piperazine

(6-bromoisochroman-1-yl)acetic acid