8-iso-PGF2beta

Base Information

• Chemical Name: 8-iso-PGF2beta
• CAS No.: 177020-26-7
• Molecular Formula: C20H34 O5
• Molecular Weight: 354.48
• DSSTox Substance ID: DTXSID401160411
• Nikkaji Number: J1.068.161H
• Metabolomics Workbench ID: 2822
• Mol file: 177020-26-7.mol

Synonyms:8-iso-PGF(2beta);8-iso-PGF2beta;8-isoprostaglandin PGF2beta

Chemical Property of 8-iso-PGF2beta

Chemical Property:

• Vapor Pressure: 1.71E-13mmHg at 25°C
• Refractive Index: 1.569
• Boiling Point: 531°Cat760mmHg
• Flash Point: 289°C
• PSA: 97.99000
• Density: 1.153g/cm³
• LogP: 3.04290
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 12
• Exact Mass: 354.24062418
• Heavy Atom Count: 25
• Complexity: 432

Purity/Quality:

98%Min ^*data from raw suppliers

8-iso Prostaglandin F2β ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCC(C=CC1C(CC(C1CC=CCCCC(=O)O)O)O)O
• Isomeric SMILES: CCCCC[C@@H](/C=C/[C@H]1[C@@H](C[C@H]([C@H]1C/C=C\CCCC(=O)O)O)O)O
• Description: 8-iso Prostaglandin F2β (8-iso PGF2β) is an isomer of PGF2α with a non-enzymatic, non-cyclooxygenase origin. It is one of 64 possible isomers of PGF2α which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF2β exhibits very weak contraction of human umbilical vein artery and does not promote aggregation of human whole blood. However, 8-iso PGF2β moderately contracts both the canine and porcine pulmonary vein, although the effect is much weaker than that exhibited by other isoprostanes such as 8-iso PGE1, 8-iso PGE2, or 8-iso PGF2α