(S)-3-BOC-AMINO-BUTYLAMINE

Base Information

Chemical Name:(S)-3-BOC-AMINO-BUTYLAMINE
CAS No.:176982-57-3
Molecular Formula:C9H20N2O2
Molecular Weight:188.27
Hs Code.:2924199090
Mol file:176982-57-3.mol

Synonyms:Carbamic acid,[(1S)-3-amino-1-methylpropyl]-, 1,1-dimethylethyl ester (9CI);Carbamicacid, (3-amino-1-methylpropyl)-, 1,1-dimethylethyl ester, (S)-;

Suppliers and Price of (S)-3-BOC-AMINO-BUTYLAMINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-3-Boc-Amino-butylamineHydrochloride
250mg
$ 135.00

Medical Isotopes, Inc.
tert-Butyl(S)-(4-aminobutan-2-yl)carbamate
5 g
$ 950.00

Matrix Scientific
(S)-tert-Butyl4-aminobutan-2-ylcarbamate 97%
25g
$ 6292.00

Matrix Scientific
(S)-tert-Butyl4-aminobutan-2-ylcarbamate 97%
5g
$ 2098.00

J&W Pharmlab
(S)-3-Boc-amino-butylaminehydrochloride 97%
100mg
$ 149.00

J&W Pharmlab
(S)-3-Boc-amino-butylamine 97%
100mg
$ 149.00

Crysdot
(S)-tert-Butyl(4-aminobutan-2-yl)carbamate 97%
1g
$ 530.00

Biosynth Carbosynth
(S)-3-Boc-amino-butylamine
100 mg
$ 104.00

Biosynth Carbosynth
(S)-3-Boc-amino-butylamine
50 mg
$ 60.00

Biosynth Carbosynth
(S)-3-Boc-amino-butylamine
500 mg
$ 360.00

Total 24 raw suppliers

Chemical Property of (S)-3-BOC-AMINO-BUTYLAMINE

Chemical Property:

Vapor Pressure:0.00333mmHg at 25°C
Refractive Index:1.455
Boiling Point:282.6 °C at 760 mmHg
Flash Point:124.7 °C
PSA：64.35000
Density:0.972g/cm³
LogP:2.33960
Storage Temp.:2-8°C(protect from light)
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

(S)-3-Boc-Amino-butylamineHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (S)-3-Boc-Amino-butylamine Hydrochloride, is used to prepare macrocyclic Hsp90 inhibitors as metabolically stabile potential antitumor agents.

Technology Process of (S)-3-BOC-AMINO-BUTYLAMINE

There total 4 articles about (S)-3-BOC-AMINO-BUTYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 172695-22-6,194156-55-3
(2-cyano-1(S)-methylethyl)carbamic acid, 1,1-dimethylethyl ester

: 176982-57-3,177489-90-6
(3-amino-1(S)-methylpropyl)carbamic acid, 1,1-dimethylethyl ester

Guidance literature:: With ammonia; hydrogen; nickel; In ethanol; at 20 ℃; for 15h; under 4500.36 Torr;
DOI:10.1021/jm991043x

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 176982-57-3,177489-90-6
(3-amino-1(S)-methylpropyl)carbamic acid, 1,1-dimethylethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / tetrahydrofuran / 1 h / 20 °C

2: 86 percent / Et₃N / CH₂Cl₂ / 2 h / 20 °C

3: 72 percent / dimethylsulfoxide / 15 h / 40 - 45 °C

4: 94 percent / H₂; NH₃ / Raney Ni / ethanol / 15 h / 20 °C / 4500.36 Torr

With ammonia; hydrogen; triethylamine; nickel; In tetrahydrofuran; ethanol; dichloromethane; dimethyl sulfoxide; 1: tert-Butyloxycarbonylation / 2: Mesylation / 3: Substitution / 4: Catalytic hydrogenation;
DOI:10.1021/jm991043x

Reference yield:

: 79069-13-9
(S)-2-t-butoxycarbonylaminopropan-1-ol

: 176982-57-3,177489-90-6
(3-amino-1(S)-methylpropyl)carbamic acid, 1,1-dimethylethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / Et₃N / CH₂Cl₂ / 2 h / 20 °C

2: 72 percent / dimethylsulfoxide / 15 h / 40 - 45 °C

3: 94 percent / H₂; NH₃ / Raney Ni / ethanol / 15 h / 20 °C / 4500.36 Torr

With ammonia; hydrogen; triethylamine; nickel; In ethanol; dichloromethane; dimethyl sulfoxide; 1: Mesylation / 2: Substitution / 3: Catalytic hydrogenation;
DOI:10.1021/jm991043x