Technology Process of (3S)-5-(benzyloxy)-3-methylpentanal
There total 20 articles about (3S)-5-(benzyloxy)-3-methylpentanal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(S)-(+)-5,5-dimethoxy-3-methyl-1-pentanol;
With
sodium hydride;
In
tetrahydrofuran;
for 0.333333h;
benzyl chloride;
In
tetrahydrofuran;
at 50 ℃;
for 8h;
With
pyridinium p-toluenesulfonate;
In
water; acetone;
for 4h;
Heating;
DOI:10.1134/S1070428013020127
- Guidance literature:
-
C14H20O;
With
osmium(VIII) oxide; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; water; tert-butyl alcohol;
for 12h;
Inert atmosphere;
With
sodium periodate;
In
methanol; water;
at 0 - 20 ℃;
for 3h;
Inert atmosphere;
DOI:10.1021/ol302309c
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tri-n-butyl-tin hydride; 2,2'-azobis(isobutyronitrile) / toluene / 12 h / Reflux; Inert atmosphere
2.1: 4-methylmorpholine N-oxide; osmium(VIII) oxide / tert-butyl alcohol; water; tetrahydrofuran / 12 h / Inert atmosphere
2.2: 3 h / 0 - 20 °C / Inert atmosphere
With
osmium(VIII) oxide; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; water; toluene; tert-butyl alcohol;
1.1: |Barton-McCombie Deoxygenation;
DOI:10.1021/ol302309c
