3,6-difluorophtalimide

Base Information

• Chemical Name: 3,6-difluorophtalimide
• CAS No.: 1416074-03-7
• Molecular Formula: C₈H₆F₂N₂O₂
• Molecular Weight: 200.145
• Mol file: 1416074-03-7.mol

Synonyms:3,6-difluorophtalimide

Chemical Property of 3,6-difluorophtalimide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,6-difluorophtalimide

There total 5 articles about 3,6-difluorophtalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

3,6-difluorophtalimide (196956-23-7) → 3,6-difluorophtalimide (1416074-03-7)

Guidance literature:

With ammonia; In water; for 48h;

DOI:10.1055/s-0031-1290462

Reference yield:

2,5-difluorobenzoyl chloride (35730-09-7) → 3,6-difluorophtalimide (1416074-03-7)

Guidance literature:

Multi-step reaction with 5 steps

1: diethylamine

2: n-butyllithium; carbon dioxide; water

3: water; sulfuric acid / Reflux

4: urea / 4 h / 125 - 130 °C

5: ammonia / water / 48 h

With n-butyllithium; carbon dioxide; ammonia; water; diethylamine; urea; In sulfuric acid; water;

DOI:10.1055/s-0031-1290462

Reference yield:

2,5-difluoro-N,N-diethylbenzamide (131401-55-3) → 3,6-difluorophtalimide (1416074-03-7)

Guidance literature:

Multi-step reaction with 4 steps

1: n-butyllithium; carbon dioxide; water

2: water; sulfuric acid / Reflux

3: urea / 4 h / 125 - 130 °C

4: ammonia / water / 48 h

With n-butyllithium; carbon dioxide; ammonia; water; urea; In sulfuric acid; water;

DOI:10.1055/s-0031-1290462

upstream raw materials:

3,6-difluorophtalimide

2,5-difluorobenzoyl chloride

2,5-difluoro-N,N-diethylbenzamide

2-<(diethylamino)carbonyl>-3,6-difluorobenzoic acid