diethyl 5-(N,N-diphenylamino)isophthalate

Base Information

• Chemical Name: diethyl 5-(N,N-diphenylamino)isophthalate
• CAS No.: 710349-77-2
• Molecular Formula: C₂₄H₂₃NO₄
• Molecular Weight: 389.451
• Mol file: 710349-77-2.mol

Synonyms:diethyl 5-(N,N-diphenylamino)isophthalate

Chemical Property of diethyl 5-(N,N-diphenylamino)isophthalate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethyl 5-(N,N-diphenylamino)isophthalate

There total 2 articles about diethyl 5-(N,N-diphenylamino)isophthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.5%

iodobenzene (591-50-4) + diethyl 5-aminoisophthalate (42122-73-6) → diethyl 5-(N,N-diphenylamino)isophthalate (710349-77-2)

Guidance literature:

With copper; potassium carbonate; at 175 - 180 ℃; for 120h;

DOI:10.1021/ma0494232

Reference yield:

5-aminoisophthalic acid (99-31-0) → diethyl 5-(N,N-diphenylamino)isophthalate (710349-77-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / SOCl₂ / 72 h / 20 °C

2: 64.5 percent / potassium carbonate; copper / 120 h / 175 - 180 °C

With thionyl chloride; copper; potassium carbonate;

DOI:10.1021/ma0494232

Reference yield: 86.0%

diethyl 5-(N,N-diphenylamino)isophthalate (710349-77-2) → 1,3-bis(hydroxymethyl)-5-(N,N-diphenylamino)benzene (710349-78-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 4h; Heating;

DOI:10.1021/ma0494232

upstream raw materials:

iodobenzene

diethyl 5-aminoisophthalate

5-aminoisophthalic acid

Downstream raw materials:

1,3-bis(hydroxymethyl)-5-(N,N-diphenylamino)benzene

5-(N,N-diphenylamino)benzene-1,3-dicarbaldehyde