4-bromo-2-octylaniline

Base Information

• Chemical Name: 4-bromo-2-octylaniline
• CAS No.: 1415385-19-1
• Molecular Formula: C₁₄H₂₂BrN
• Molecular Weight: 284.239
• Mol file: 1415385-19-1.mol

Synonyms:4-bromo-2-octylaniline

Chemical Property of 4-bromo-2-octylaniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-bromo-2-octylaniline

There total 5 articles about 4-bromo-2-octylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2-octylaniline (37413-50-6) → 4-bromo-2-octylaniline (1415385-19-1)

Guidance literature:

With pyridinium hydrobromide perbromide; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1021/acs.joc.9b01046

Reference yield:

n-octyne (629-05-0) → 4-bromo-2-octylaniline (1415385-19-1)

Guidance literature:

Multi-step reaction with 3 steps

1: bis(diphenylphosphino)palladium(II)dichloride; diethylamine; copper(l) iodide / N,N-dimethyl-formamide / 3 h / 20 °C

2: hydrogen; palladium on activated charcoal / methanol / 24 h / 20 °C

3: Mo₇O₂₄^(6-)*2H₄N⁽¹⁺⁾*7H₂O; potassium bromide; acetic acid; sodium perborate / 6 h / 20 °C

With sodium perborate; copper(l) iodide; bis(diphenylphosphino)palladium(II)dichloride; palladium on activated charcoal; Mo₇O₂₄^(6-)*2H₄N⁽¹⁺⁾*7H₂O; hydrogen; acetic acid; diethylamine; potassium bromide; In methanol; N,N-dimethyl-formamide;

DOI:10.1002/anie.201206096

Reference yield:

2-iodophenylamine (615-43-0) → 4-bromo-2-octylaniline (1415385-19-1)

Guidance literature:

Multi-step reaction with 3 steps

1: bis(diphenylphosphino)palladium(II)dichloride; diethylamine; copper(l) iodide / N,N-dimethyl-formamide / 3 h / 20 °C

2: hydrogen; palladium on activated charcoal / methanol / 24 h / 20 °C

3: Mo₇O₂₄^(6-)*2H₄N⁽¹⁺⁾*7H₂O; potassium bromide; acetic acid; sodium perborate / 6 h / 20 °C

With sodium perborate; copper(l) iodide; bis(diphenylphosphino)palladium(II)dichloride; palladium on activated charcoal; Mo₇O₂₄^(6-)*2H₄N⁽¹⁺⁾*7H₂O; hydrogen; acetic acid; diethylamine; potassium bromide; In methanol; N,N-dimethyl-formamide;

DOI:10.1002/anie.201206096

upstream raw materials:

n-octyne

2-iodophenylamine

2-octylaniline

2-nitrophenyl bromide

Downstream raw materials:

4-bromo-1-iodo-2-octylbenzene