(2S,3R)-2-benzyloxy-4-{(2R,6S)-6-[(3S,5R,7S,10R,Z)-10-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-7-hydroxy-5-methoxy-2,8-dimethyldodec-8-en-2-yl] tetrahydro-2H-pyran-2-yl}-3-methoxybutanoic acid

Base Information

Chemical Name:(2S,3R)-2-benzyloxy-4-{(2R,6S)-6-[(3S,5R,7S,10R,Z)-10-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-7-hydroxy-5-methoxy-2,8-dimethyldodec-8-en-2-yl] tetrahydro-2H-pyran-2-yl}-3-methoxybutanoic acid
CAS No.:1466415-40-6
Molecular Formula:C₄₆H₇₄O₉Si
Molecular Weight:799.174
Hs Code.:

(2S,3R)-2-benzyloxy-4-{(2R,6S)-6-[(3S,5R,7S,10R,Z)-10-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-7-hydroxy-5-methoxy-2,8-dimethyldodec-8-en-2-yl] tetrahydro-2H-pyran-2-yl}-3-methoxybutanoic acid

Synonyms:(2S,3R)-2-benzyloxy-4-{(2R,6S)-6-[(3S,5R,7S,10R,Z)-10-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-7-hydroxy-5-methoxy-2,8-dimethyldodec-8-en-2-yl] tetrahydro-2H-pyran-2-yl}-3-methoxybutanoic acid

Suppliers and Price of (2S,3R)-2-benzyloxy-4-{(2R,6S)-6-[(3S,5R,7S,10R,Z)-10-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-7-hydroxy-5-methoxy-2,8-dimethyldodec-8-en-2-yl] tetrahydro-2H-pyran-2-yl}-3-methoxybutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R)-2-benzyloxy-4-{(2R,6S)-6-[(3S,5R,7S,10R,Z)-10-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-7-hydroxy-5-methoxy-2,8-dimethyldodec-8-en-2-yl] tetrahydro-2H-pyran-2-yl}-3-methoxybutanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R)-2-benzyloxy-4-{(2R,6S)-6-[(3S,5R,7S,10R,Z)-10-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-7-hydroxy-5-methoxy-2,8-dimethyldodec-8-en-2-yl] tetrahydro-2H-pyran-2-yl}-3-methoxybutanoic acid

There total 5 articles about (2S,3R)-2-benzyloxy-4-{(2R,6S)-6-[(3S,5R,7S,10R,Z)-10-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-7-hydroxy-5-methoxy-2,8-dimethyldodec-8-en-2-yl] tetrahydro-2H-pyran-2-yl}-3-methoxybutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1466415-39-3
(4S,5R)-3-{(2S,3R)-2-benzyloxy-4-[(2R,6S)-6-((3S,5R,7S,10R,Z)-10-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-7-hydroxy-5-methoxy-2,8-dimethyldodec-8-en-2-yl)tetrahydro-2H-pyran-2-yl]-3-methoxybutanoyl}-4-methyl-5-phenyloxazolidin-2-one

: 1466415-40-6
(2S,3R)-2-benzyloxy-4-{(2R,6S)-6-[(3S,5R,7S,10R,Z)-10-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-7-hydroxy-5-methoxy-2,8-dimethyldodec-8-en-2-yl] tetrahydro-2H-pyran-2-yl}-3-methoxybutanoic acid

Guidance literature:: With lithium hydroxide monohydrate; dihydrogen peroxide; In tetrahydrofuran; water; at 0 ℃; for 1.25h;
DOI:10.1002/chem.201301796

Reference yield:

: 1466415-28-0
(3R,6S,8R,10S,Z)-3-(benzyloxymethyl)-10-(tert-butyldimethylsilyloxy)-11-((2S,6R)-6-(2-(tert-butyldiphenylsilyloxy)ethyl)tetrahydro-2H-pyran-2-yl)-8-methoxy-5,11-dimethyldodec-4-en-6-ol

: 1466415-40-6
(2S,3R)-2-benzyloxy-4-{(2R,6S)-6-[(3S,5R,7S,10R,Z)-10-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-7-hydroxy-5-methoxy-2,8-dimethyldodec-8-en-2-yl] tetrahydro-2H-pyran-2-yl}-3-methoxybutanoic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: pyridinium p-toluenesulfonate / dichloromethane / 6 h / 20 °C

2.1: sodium hydroxide / tetrahydrofuran; methanol / 16 h / 67 °C

3.1: Dess-Martin periodane / dichloromethane / 1.75 h / 0 °C

4.1: di-n-butylboryl trifluoromethanesulfonate; triethylamine / dichloromethane / 2 h / -78 - 0 °C

4.2: 2.5 h / -78 °C

5.1: dihydrogen peroxide; lithium hydroxide monohydrate / tetrahydrofuran; water / 1.25 h / 0 °C

With lithium hydroxide monohydrate; di-n-butylboryl trifluoromethanesulfonate; dihydrogen peroxide; pyridinium p-toluenesulfonate; Dess-Martin periodane; triethylamine; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1002/chem.201301796

Reference yield:

: 2-{(2R,6S)-6-[(3S,5R,7S,10R,Z)-10-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-5-methoxy-2,8-dimethyl-7-(tetrahydro-2H-pyran-2-yloxy)dodec-8-en-2-yl]tetrahydro-2H-pyran-2-yl}ethanol

: 1466415-40-6
(2S,3R)-2-benzyloxy-4-{(2R,6S)-6-[(3S,5R,7S,10R,Z)-10-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-7-hydroxy-5-methoxy-2,8-dimethyldodec-8-en-2-yl] tetrahydro-2H-pyran-2-yl}-3-methoxybutanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: Dess-Martin periodane / dichloromethane / 1.75 h / 0 °C

2.1: di-n-butylboryl trifluoromethanesulfonate; triethylamine / dichloromethane / 2 h / -78 - 0 °C

2.2: 2.5 h / -78 °C

3.1: dihydrogen peroxide; lithium hydroxide monohydrate / tetrahydrofuran; water / 1.25 h / 0 °C

With lithium hydroxide monohydrate; di-n-butylboryl trifluoromethanesulfonate; dihydrogen peroxide; Dess-Martin periodane; triethylamine; In tetrahydrofuran; dichloromethane; water;
DOI:10.1002/chem.201301796