C₁₆H₂₀O₂

Base Information

• Chemical Name: C₁₆H₂₀O₂
• CAS No.: 1338347-32-2
• Molecular Formula: C₁₆H₂₀O₂
• Molecular Weight: 244.334
• Mol file: 1338347-32-2.mol

Synonyms:C₁₆H₂₀O₂

Chemical Property of C₁₆H₂₀O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₂₀O₂

There total 4 articles about C₁₆H₂₀O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

C21H28O3 (1338347-50-4) → C16H20O2 (1338347-32-2)

Guidance literature:

With hydrogenchloride; water; In methanol; at 23 ℃; for 3h; Inert atmosphere;

DOI:10.1021/ol202649j

Reference yield:

C20H26O3 → C16H20O2 (1338347-32-2)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran; hexane / 12 h / 23 °C / Inert atmosphere

2: hydrogenchloride; water / methanol / 3 h / 23 °C / Inert atmosphere

With hydrogenchloride; water; In tetrahydrofuran; methanol; hexane;

DOI:10.1021/ol202649j

Reference yield:

hex-1-en-5-yn-3-ol (1573-66-6) → C16H20O2 (1338347-32-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: toluene-4-sulfonic acid / dichloromethane / 0 - 23 °C / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere

2.2: -78 - 23 °C / Inert atmosphere

3.1: tetrahydrofuran; hexane / 12 h / 23 °C / Inert atmosphere

4.1: hydrogenchloride; water / methanol / 3 h / 23 °C / Inert atmosphere

With hydrogenchloride; n-butyllithium; water; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; hexane; dichloromethane;

DOI:10.1021/ol202649j

upstream raw materials:

C₂₁H₂₈O₃

hex-1-en-5-yn-3-ol

3-(tetrahydropyran-2-yloxy)hex-1-en-5-yne

Downstream raw materials:

C₁₅H₁₆O

Refernces