2-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-1-isoquinolone

Base Information

Chemical Name:2-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-1-isoquinolone
CAS No.:600707-57-1
Molecular Formula:C₃₆H₃₃NO₇
Molecular Weight:591.661
Hs Code.:

Synonyms:2-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-1-isoquinolone

Suppliers and Price of 2-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-1-isoquinolone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-1-isoquinolone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-1-isoquinolone

There total 5 articles about 2-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-1-isoquinolone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 402859-75-0
2-(2-O,4-C-methylene-β-D-ribofuranosyl)-1-isoquinolone

: 600707-57-1
2-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-1-isoquinolone

Guidance literature:: With pyridine; at 20 ℃; for 3h;
DOI:10.1016/S0040-4020(03)00728-2

Reference yield:

: 491-30-5
1-isoquinolone

: 600707-57-1
2-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-1-isoquinolone

Guidance literature:: Multi-step reaction with 4 steps

1.1: N,O-bis(trimethylsilyl)acetamide / 1,2-dichloro-ethane / 1 h / Heating

1.2: 83 percent / trimethylsilyl trifluoromethanesulfonate / 1,2-dichloro-ethane / 2 h / Heating

2.1: 95 percent / K₂CO₃ / methanol / 9 h / 20 °C

3.1: 95 percent / cyclohexene / Pd(OH)2/C / ethanol / 1 h / Heating

4.1: 100 percent / pyridine / 3 h / 20 °C

With pyridine; N,O-bis-(trimethylsilyl)-acetamide; potassium carbonate; cyclohexene; palladium dihydroxide; In methanol; ethanol; 1,2-dichloro-ethane;
DOI:10.1016/S0040-4020(03)00728-2

Reference yield:

: 209968-86-5
4-C-[(phenylmethoxy)methyl]-3-O-(phenylmethyl)-1,2-diacetate 5-(4-methylbenzenesulfonate)-L-lyxofuranose

: 600707-57-1
2-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-1-isoquinolone

Guidance literature:: Multi-step reaction with 4 steps

1.1: N,O-bis(trimethylsilyl)acetamide / 1,2-dichloro-ethane / 1 h / Heating

1.2: 83 percent / trimethylsilyl trifluoromethanesulfonate / 1,2-dichloro-ethane / 2 h / Heating

2.1: 95 percent / K₂CO₃ / methanol / 9 h / 20 °C

3.1: 95 percent / cyclohexene / Pd(OH)2/C / ethanol / 1 h / Heating

4.1: 100 percent / pyridine / 3 h / 20 °C

With pyridine; N,O-bis-(trimethylsilyl)-acetamide; potassium carbonate; cyclohexene; palladium dihydroxide; In methanol; ethanol; 1,2-dichloro-ethane;
DOI:10.1016/S0040-4020(03)00728-2