Technology Process of C16H14N4O2
There total 6 articles about C16H14N4O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(II) sulfate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine;
In
methanol; water;
at 20 ℃;
for 24h;
Combinatorial reaction / High throughput screening (HTS);
DOI:10.1021/jm300837y
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydroxide; water / methanol / 5 h / 0 - 20 °C
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 24 h / 20 °C
3: toluene-4-sulfonic acid / methanol / 12 h / 20 °C
4: copper(II) sulfate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; sodium L-ascorbate / water; methanol / 24 h / 20 °C / Combinatorial reaction / High throughput screening (HTS)
With
water; benzotriazol-1-ol; toluene-4-sulfonic acid; copper(II) sulfate; sodium L-ascorbate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine;
In
methanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jm300837y
- Guidance literature:
-
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / methanol / 12 h / 20 °C
2: copper(II) sulfate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; sodium L-ascorbate / water; methanol / 24 h / 20 °C / Combinatorial reaction / High throughput screening (HTS)
With
toluene-4-sulfonic acid; copper(II) sulfate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine;
In
methanol; water;
DOI:10.1021/jm300837y