(1R,2R,5S,6R)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid

Base Information

Chemical Name:(1R,2R,5S,6R)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
CAS No.:176199-49-8
Molecular Formula:C₈H₁₁NO₄
Molecular Weight:185.18
Hs Code.:
DSSTox Substance ID:DTXSID90443684
Nikkaji Number:J812.965G
Wikidata:Q82261588
Mol file:176199-49-8.mol

Synonyms:176199-49-8;(1R,2R,5S,6R)-2-AMINOBICYCLO[3.1.0]HEXANE-2,6-DICARBOXYLIC ACID;Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1R,2R,5S,6R)- (9CI);CTK0H1086;176027-90-0;DTXSID90443684;VTAARTQTOOYTES-AFCXAGJDSA-N;(1beta,5beta)-2alpha-Aminobicyclo[3.1.0]hexane-2,6beta-dicarboxylic acid;rel-(1R,2R,5S,6R)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid;rel-(1R,2R,5S,6R)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylicacid

Suppliers and Price of (1R,2R,5S,6R)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (1R,2R,5S,6R)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid

Chemical Property:

PSA：100.62000
LogP:0.20940
XLogP3:-3.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:185.06880783
Heavy Atom Count:13
Complexity:290

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C2C1C2C(=O)O)(C(=O)O)N
Isomeric SMILES:C1C[C@@]([C@@H]2[C@H]1[C@H]2C(=O)O)(C(=O)O)N

Technology Process of (1R,2R,5S,6R)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid

There total 38 articles about (1R,2R,5S,6R)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: (-)-bicyclo[3.1.0]hexane-6-carboxylate-2-spiro-5'-hydantoin

: 176027-90-0,176199-49-8,177317-28-1,207553-80-8,597540-64-2
(+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid

Guidance literature:: With sodium hydroxide; for 28h; Heating;
DOI:10.1021/jm9606756

Reference yield: 85.0%

: 188885-88-3
(1S,2S,5R,6S)-ethyl 2-spirohydantoin-bicyclo[3.1.0]hexane-6-carboxylate

: 176199-48-7,176027-90-0,176199-49-8,177317-28-1,207553-80-8,597540-64-2
eglumetad

Guidance literature:: (1S,2S,5R,6S)-ethyl 2-spirohydantoin-bicyclo[3.1.0]hexane-6-carboxylate; With sodium hydroxide; for 28h; Reflux;

With hydrogenchloride; In water; at 0 - 20 ℃; for 3h; pH=3;
DOI:10.1016/j.tetasy.2010.04.051