(R)-methyl 2-methylene-4,4-bis(phenylsulfonyl)-3-(4-(trifluoromethyl)phenyl)butanoate

Base Information

Chemical Name:(R)-methyl 2-methylene-4,4-bis(phenylsulfonyl)-3-(4-(trifluoromethyl)phenyl)butanoate
CAS No.:1322591-91-2
Molecular Formula:C₂₅H₂₁F₃O₆S₂
Molecular Weight:538.565
Hs Code.:

Synonyms:(R)-methyl 2-methylene-4,4-bis(phenylsulfonyl)-3-(4-(trifluoromethyl)phenyl)butanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-methyl 2-methylene-4,4-bis(phenylsulfonyl)-3-(4-(trifluoromethyl)phenyl)butanoate

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Technology Process of (R)-methyl 2-methylene-4,4-bis(phenylsulfonyl)-3-(4-(trifluoromethyl)phenyl)butanoate

There total 1 articles about (R)-methyl 2-methylene-4,4-bis(phenylsulfonyl)-3-(4-(trifluoromethyl)phenyl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 3406-02-8
bis(phenylsulfonyl)methane

: 1322591-74-1
methyl 2-(((tert-butoxycarbonyl)oxy)(4-(trifluoromethyl)phenyl)methyl)acrylate

: 1322591-91-2
(R)-methyl 2-methylene-4,4-bis(phenylsulfonyl)-3-(4-(trifluoromethyl)phenyl)butanoate

Guidance literature:: With hydroquinidine (anthraquinone-1,4-diyl) diether; In toluene; at 20 ℃; for 96h; optical yield given as %ee; enantioselective reaction;
DOI:10.1039/c1ob06308a

Reference yield:

: 1322591-91-2
(R)-methyl 2-methylene-4,4-bis(phenylsulfonyl)-3-(4-(trifluoromethyl)phenyl)butanoate

: (3S)-methyl 2-methyl-4,4-bis(phenylsulfonyl)-3-(4-(trifluoromethyl)phenyl)butanoate

: (3S)-methyl 2-methyl-4,4-bis(phenylsulfonyl)-3-(4-(trifluoromethyl)phenyl)butanoate

Guidance literature:: With palladium on carbon; hydrogen; In ethyl acetate; at 20 ℃; optical yield given as %de; diastereoselective reaction;
DOI:10.1039/c1ob06308a