(E)-(2S,5R,6R)-8-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-5-methyl-oct-3-en-2-ol

Base Information

Chemical Name:(E)-(2S,5R,6R)-8-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-5-methyl-oct-3-en-2-ol
CAS No.:713141-49-2
Molecular Formula:C₃₁H₅₀O₃Si₂
Molecular Weight:526.907
Hs Code.:

Synonyms:(E)-(2S,5R,6R)-8-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-5-methyl-oct-3-en-2-ol

Suppliers and Price of (E)-(2S,5R,6R)-8-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-5-methyl-oct-3-en-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (E)-(2S,5R,6R)-8-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-5-methyl-oct-3-en-2-ol

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-(2S,5R,6R)-8-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-5-methyl-oct-3-en-2-ol

There total 1 articles about (E)-(2S,5R,6R)-8-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-5-methyl-oct-3-en-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 8-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-5-methyl-oct-3-en-2-one

: 713141-49-2
(E)-(2S,5R,6R)-8-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-5-methyl-oct-3-en-2-ol

: (E)-(2R,5R,6R)-8-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-5-methyl-oct-3-en-2-ol

Guidance literature:: With dimethylsulfide borane complex; (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole; In dichloromethane;
DOI:10.3987/COM-04-10034

Reference yield: 88.0%

: 110-87-2
3,4-dihydro-2H-pyran

: 713141-49-2
(E)-(2S,5R,6R)-8-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-5-methyl-oct-3-en-2-ol

: 713141-50-5
2-[(E)-(1S,4R,5R)-7-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxy)-1,4-dimethyl-hept-2-enyloxy]-tetrahydro-pyran

Guidance literature:: With toluene-4-sulfonic acid; In dichloromethane;
DOI:10.3987/COM-04-10034

Reference yield:

: 713141-49-2
(E)-(2S,5R,6R)-8-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-5-methyl-oct-3-en-2-ol

: 713141-54-9
(4R,5R,6S)-4-(tert-Butyl-diphenyl-silanyloxy)-5-methyl-6-((E)-propenyl)-tetrahydro-pyran-2-one

Guidance literature:: Multi-step reaction with 5 steps

1.1: 88 percent / p-TsOH / CH₂Cl₂

2.1: 62 percent / HF*pyridine / tetrahydrofuran

3.1: 87 percent / IBX; DMSO / tetrahydrofuran

4.1: 80 percent / PdCl₂(PhCN)2 / methanol; tetrahydrofuran

5.1: aq. AcOH / 70 °C

5.2: 61 percent / IBX; DMSO / tetrahydrofuran

With toluene-4-sulfonic acid; pyridine hydrogenfluoride; acetic acid; dimethyl sulfoxide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; bis(benzonitrile)palladium(II) dichloride; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.3987/COM-04-10034