Apigen-4'7-diyl-di(2,3,4,6-tetra-O-acetyl-β-D-glucopranoside)

Base Information

• Chemical Name: Apigen-4'7-diyl-di(2,3,4,6-tetra-O-acetyl-β-D-glucopranoside)
• CAS No.: 130999-29-0
• Molecular Formula: C₄₃H₄₆O₂₃
• Molecular Weight: 930.824
• Mol file: 130999-29-0.mol

Synonyms:Apigen-4'7-diyl-di(2,3,4,6-tetra-O-acetyl-β-D-glucopranoside)

Chemical Property of Apigen-4'7-diyl-di(2,3,4,6-tetra-O-acetyl-β-D-glucopranoside)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Apigen-4'7-diyl-di(2,3,4,6-tetra-O-acetyl-β-D-glucopranoside)

There total 7 articles about Apigen-4'7-diyl-di(2,3,4,6-tetra-O-acetyl-β-D-glucopranoside) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2,3,4,6-tetra-O-acetyl-α,β-D-glucopyranosyl fluoride (162489-61-4) + 7-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)apigenin (119249-30-8) → Apigen-4'7-diyl-di(2,3,4,6-tetra-O-acetyl-β-D-glucopranoside) (130999-29-0)

Guidance literature:

With 2,6-di-tert-butyl-4-methylpyridine; boron trifluoride diethyl etherate; N,N,N',N'-tetramethylguanidine; In dichloromethane; chlorobenzene;

DOI:10.1002/1521-3773(20010302)40:5<894::AID-ANIE894>3.0.CO;2-8

Reference yield: 70.0%

7-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)apigenin (119249-30-8) + 2,3,4,6-tetra-O-acetyl-1-fluoro-α-D-glucopyranose (439-03-2,439-04-3,439-05-4,2823-44-1,2823-46-3,3934-29-0,4163-44-4,4163-45-5,20409-31-8,23235-96-3,51897-75-7,51897-76-8,51897-77-9,57573-38-3,62561-28-8,126641-47-2) → Apigen-4'7-diyl-di(2,3,4,6-tetra-O-acetyl-β-D-glucopranoside) (130999-29-0)

Guidance literature:

With 2,6-di-tert-butyl-4-methylpyridine; boron trifluoride diethyl etherate; N,N,N',N'-tetramethylguanidine; In dichloromethane; chlorobenzene; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2004.01.001

Reference yield: 20.0%

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one (520-36-5) + 3-O-(2'',3'',4'',6''-tetra-O-acetyl-β-D-glucopyranosyl)-4',7-di-O-benzyl-3',5-dihydroxyflavonol (131021-81-3) → Apigen-4'7-diyl-di(2,3,4,6-tetra-O-acetyl-β-D-glucopranoside) (130999-29-0)

Guidance literature:

With potassium hydroxide; benzyltriethylammonium bromide; In chloroform; at 60 ℃; for 15h;

DOI:10.1016/0008-6215(90)80012-R

upstream raw materials:

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

3-O-(2'',3'',4'',6''-tetra-O-acetyl-β-D-glucopyranosyl)-4',7-di-O-benzyl-3',5-dihydroxyflavonol

2,3,4,6-tetra-O-acetyl-α,β-D-glucopyranosyl fluoride

7-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)apigenin