[(1R)-2-methyl-1-phenyl-2-(1-pyrrolidinyl)propyl]-R-(+)-α-methylbenzylamine

Base Information

Chemical Name:[(1R)-2-methyl-1-phenyl-2-(1-pyrrolidinyl)propyl]-R-(+)-α-methylbenzylamine
CAS No.:960524-32-7
Molecular Formula:C₂₂H₃₀N₂
Molecular Weight:322.494
Hs Code.:

Synonyms:[(1R)-2-methyl-1-phenyl-2-(1-pyrrolidinyl)propyl]-R-(+)-α-methylbenzylamine

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Chemical Property of [(1R)-2-methyl-1-phenyl-2-(1-pyrrolidinyl)propyl]-R-(+)-α-methylbenzylamine

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Technology Process of [(1R)-2-methyl-1-phenyl-2-(1-pyrrolidinyl)propyl]-R-(+)-α-methylbenzylamine

There total 1 articles about [(1R)-2-methyl-1-phenyl-2-(1-pyrrolidinyl)propyl]-R-(+)-α-methylbenzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 960524-31-6
2-pyrrolidinyl-2-methylpropiophenone

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 960524-32-7
[(1R)-2-methyl-1-phenyl-2-(1-pyrrolidinyl)propyl]-R-(+)-α-methylbenzylamine

Guidance literature:: 2-pyrrolidinyl-2-methylpropiophenone; (R)-1-phenyl-ethyl-amine; With titanium tetrachloride; triethylamine; In dichloromethane; acetonitrile; at 10 - 20 ℃; Inert atmosphere;

With methanol; sodium tetrahydroborate; In dichloromethane; acetonitrile; at 0 - 20 ℃; Product distribution / selectivity;

Reference yield: 76.0%

: 960524-32-7
[(1R)-2-methyl-1-phenyl-2-(1-pyrrolidinyl)propyl]-R-(+)-α-methylbenzylamine

: 896119-96-3
(R)-(+)-[2-methyl-1-phenyl-2-(1-pyrrolidinyl)propyl]amine

Guidance literature:: [(1R)-2-methyl-1-phenyl-2-(1-pyrrolidinyl)propyl]-R-(+)-α-methylbenzylamine; With sulfuric acid; hydrogen; palladium 10% on activated carbon; In methanol; at 60 ℃; for 1h; under 2280.15 Torr;

With sodium hydroxide; In water; pH=12 - 13; Product distribution / selectivity;