1-<4-(hydroxymethyl)phenoxy>-4-1-(N⁴-phenlylpiperazinyl)>butane

Base Information

Chemical Name:1-<4-(hydroxymethyl)phenoxy>-4-1-(N⁴-phenlylpiperazinyl)>butane
CAS No.:127227-57-0
Molecular Formula:C₂₁H₂₈N₂O₂
Molecular Weight:340.466
Hs Code.:

1-<4-(hydroxymethyl)phenoxy>-4-<N<sup>1</sup>-(N<sup>4</sup>-phenlylpiperazinyl)>butane

Synonyms:1-<4-(hydroxymethyl)phenoxy>-4-1-(N⁴-phenlylpiperazinyl)>butane

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Chemical Property of 1-<4-(hydroxymethyl)phenoxy>-4-1-(N⁴-phenlylpiperazinyl)>butane

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Technology Process of 1-<4-(hydroxymethyl)phenoxy>-4-1-(N⁴-phenlylpiperazinyl)>butane

There total 3 articles about 1-<4-(hydroxymethyl)phenoxy>-4-1-(N⁴-phenlylpiperazinyl)>butane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 127227-55-8
4-[4-(4-Phenyl-piperazin-1-yl)-butoxy]-benzaldehyde

: 127227-57-0
1-<4-(hydroxymethyl)phenoxy>-4-1-(N⁴-phenlylpiperazinyl)>butane

Guidance literature:: With sodium tetrahydroborate; In methanol; for 4h; Ambient temperature;

Reference yield:

: 14467-68-6
1-nitro-4-(4-(4-nitrophenoxy)butoxy)benzene

: 127227-57-0
1-<4-(hydroxymethyl)phenoxy>-4-1-(N⁴-phenlylpiperazinyl)>butane

Guidance literature:: Multi-step reaction with 2 steps

1: 54 percent / 3 h / 100 °C

2: 80 percent / NaBH₄ / methanol / 4 h / Ambient temperature

With sodium tetrahydroborate; In methanol;

Reference yield:

: 824-78-2
4-nitrophenol sodium salt

: 127227-57-0
1-<4-(hydroxymethyl)phenoxy>-4-1-(N⁴-phenlylpiperazinyl)>butane

Guidance literature:: Multi-step reaction with 3 steps

1: 12.5 percent / dimethylformamide / 0.5 h

2: 54 percent / 3 h / 100 °C

3: 80 percent / NaBH₄ / methanol / 4 h / Ambient temperature

With sodium tetrahydroborate; In methanol; N,N-dimethyl-formamide;