methyl 3-((1-methylethyl){[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}amino)-2-thiophenecarboxylate

Base Information

Chemical Name:methyl 3-((1-methylethyl){[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}amino)-2-thiophenecarboxylate
CAS No.:942589-93-7
Molecular Formula:C₁₇H₂₂F₃NO₃S
Molecular Weight:377.428
Hs Code.:

Synonyms:methyl 3-((1-methylethyl){[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}amino)-2-thiophenecarboxylate

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Chemical Property of methyl 3-((1-methylethyl){[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}amino)-2-thiophenecarboxylate

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Technology Process of methyl 3-((1-methylethyl){[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}amino)-2-thiophenecarboxylate

There total 1 articles about methyl 3-((1-methylethyl){[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}amino)-2-thiophenecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 934330-05-9
trans-4-(trifluoromethyl)cyclohexanecarbonyl chloride

: 153071-59-1
methyl 3-(isopropyl-amino)thiophene-2-carboxylate

: 942589-93-7
methyl 3-((1-methylethyl){[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}amino)-2-thiophenecarboxylate

Guidance literature:: With triphenylphosphine; In dichloromethane; at 50 ℃;

Reference yield:

: 942589-93-7
methyl 3-((1-methylethyl){[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}amino)-2-thiophenecarboxylate

: 942589-94-8
methyl 5-iodo-3-((1-methylethyl){[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}amino)-2-thiophenecarboxylate

Guidance literature:: methyl 3-((1-methylethyl){[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}amino)-2-thiophenecarboxylate; With lithium diisopropyl amide; In tetrahydrofuran; n-heptane; ethylbenzene; at -80 - -70 ℃; for 1.91667h;

With iodine; In tetrahydrofuran; n-heptane; ethylbenzene; at -70 ℃; for 0.916667h;

Reference yield:

: 942589-93-7
methyl 3-((1-methylethyl){[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}amino)-2-thiophenecarboxylate

: 942590-49-0
{4-((1-methylethyl){[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}amino)-5-[(methyloxy)carbonyl]-2-thienyl}boronic acid

Guidance literature:: methyl 3-((1-methylethyl){[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}amino)-2-thiophenecarboxylate; With lithium diisopropyl amide; In tetrahydrofuran; n-heptane; ethylbenzene; at -78 ℃; for 0.75h;

With Trimethyl borate; In tetrahydrofuran; n-heptane; ethylbenzene; at -78 ℃; for 0.5h;