3-O-benzyl-1,2-O-isopropylidene-α-D-galactofuranose

Base Information

• Chemical Name: 3-O-benzyl-1,2-O-isopropylidene-α-D-galactofuranose
• CAS No.: 65434-49-3
• Molecular Formula: C₁₆H₂₂O₆
• Molecular Weight: 310.347
• Mol file: 65434-49-3.mol

Synonyms:3-O-benzyl-1,2-O-isopropylidene-α-D-galactofuranose

Chemical Property of 3-O-benzyl-1,2-O-isopropylidene-α-D-galactofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-O-benzyl-1,2-O-isopropylidene-α-D-galactofuranose

There total 10 articles about 3-O-benzyl-1,2-O-isopropylidene-α-D-galactofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-O-benzyl-1,2:5,6-di-O-isopropylidene-α-D-galactofuranose (65451-98-1) → 3-O-benzyl-1,2-O-isopropylidene-α-D-galactofuranose (65434-49-3)

Guidance literature:

With sodium hydrogen sulfate; silica gel; In dichloromethane; isopropyl alcohol; at 20 ℃; for 4h;

DOI:10.1246/cl.2003.734

Reference yield: 93.0%

C19H26O6 → 3-O-benzyl-1,2-O-isopropylidene-α-D-glucofuranose (22529-61-9,34370-88-2,40982-91-0,42926-89-6,57099-04-4,65434-49-3,134275-39-1)

Guidance literature:

With phosphotungstic acid; water; In acetonitrile; at 20 ℃; for 5h; chemoselective reaction;

DOI:10.1016/j.tetlet.2011.05.050

Reference yield:

1,2:5,6-di-O-isopropylidene-α-D-galactofuranose (10368-86-2) → 3-O-benzyl-1,2-O-isopropylidene-α-D-galactofuranose (65434-49-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / NaH / dimethylformamide

2: 87 percent / AcOH; H₂O

With water; sodium hydride; acetic acid; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(03)01098-0

upstream raw materials:

5,6-di-O-benzoyl-3-O-benzyl-1,2-O-isopropylidene-β-L-idofuranose

3-O-benzyl-1,2:5,6-di-O-isopropylidene-α-D-galactofuranose

1,2:5,6-di-O-isopropylidene-α-D-galactofuranose

3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-erythro-hex-3-enofuranose

Downstream raw materials:

5,6-di-O-acetyl-3-O-benzyl-1,2-O-isopropylidene-α-D-galactofuranose

3-O-benzyl-1,2-O-isopropylidene-6-O-(triphenylmethyl)-β-L-arabino-hexofuranos-5-ulose

3-O-benzyl-5-O-benzoyl-1,2-O-isopropylidene-6-deoxy-α-D-galactofuranose

3-O-benzyl-6-deoxy-1,2-O-isopropylidene-α-D-galactofuranose