BIPHENYL-3-CARBOTHIOIC ACID AMIDE

Base Information

• Chemical Name: BIPHENYL-3-CARBOTHIOIC ACID AMIDE
• CAS No.: 175691-91-5
• Molecular Formula: C₁₃H₁₁NS
• Molecular Weight: 213.303
• Mol file: 175691-91-5.mol

Synonyms:BIPHENYL-3-CARBOTHIOIC ACID AMIDE

Chemical Property of BIPHENYL-3-CARBOTHIOIC ACID AMIDE

Chemical Property:

• PSA: 58.11000
• LogP: 3.68810

Purity/Quality:

98%min ^*data from raw suppliers

Biphenyl-3-carbothioicAcidamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BIPHENYL-3-CARBOTHIOIC ACID AMIDE

There total 3 articles about BIPHENYL-3-CARBOTHIOIC ACID AMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-phenylbenzonitrile (24973-50-0) → <1,1'>-biphenyl-3-carbothioamide (175691-91-5)

Guidance literature:

With hydrogen sulfide; triethylamine; In pyridine; for 72h; Ambient temperature;

DOI:10.1002/ardp.19963290204

Reference yield:

3-cyanobromobenzene (6952-59-6) → <1,1'>-biphenyl-3-carbothioamide (175691-91-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / 2 M aq. Na₂CO₃ / Pd(PPh₃)4 / toluene; ethanol / 6 h / Heating

2: 99 percent / H₂S, Et₃N / pyridine / 72 h / Ambient temperature

With hydrogen sulfide; sodium carbonate; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In pyridine; ethanol; toluene;

DOI:10.1002/ardp.19963290204

Reference yield:

phenylboronic acid (98-80-6) → <1,1'>-biphenyl-3-carbothioamide (175691-91-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / 2 M aq. Na₂CO₃ / Pd(PPh₃)4 / toluene; ethanol / 6 h / Heating

2: 99 percent / H₂S, Et₃N / pyridine / 72 h / Ambient temperature

With hydrogen sulfide; sodium carbonate; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In pyridine; ethanol; toluene;

DOI:10.1002/ardp.19963290204

upstream raw materials:

3-phenylbenzonitrile

3-cyanobromobenzene

phenylboronic acid

Refernces