7-Oxabicyclo[4.1.0]hept-2-ene-3-carboxylicacid,5-hydroxy-,(1R,5R,6S)-(9CI)

Base Information

Chemical Name:7-Oxabicyclo[4.1.0]hept-2-ene-3-carboxylicacid,5-hydroxy-,(1R,5R,6S)-(9CI)
CAS No.:175546-00-6
Molecular Formula:C₇H₈O₄
Molecular Weight:156.138
Hs Code.:
Mol file:175546-00-6.mol

Synonyms:7-Oxabicyclo[4.1.0]hept-2-ene-3-carboxylicacid, 5-hydroxy-, [1R-(1a,5a,6a)]-

Suppliers and Price of 7-Oxabicyclo[4.1.0]hept-2-ene-3-carboxylicacid,5-hydroxy-,(1R,5R,6S)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 7-Oxabicyclo[4.1.0]hept-2-ene-3-carboxylicacid,5-hydroxy-,(1R,5R,6S)-(9CI)

Chemical Property:

PSA：70.06000
LogP:-0.47060

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 7-Oxabicyclo[4.1.0]hept-2-ene-3-carboxylicacid,5-hydroxy-,(1R,5R,6S)-(9CI)

There total 3 articles about 7-Oxabicyclo[4.1.0]hept-2-ene-3-carboxylicacid,5-hydroxy-,(1R,5R,6S)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

: 78844-86-7
methyl 3(R),4(R)-epoxy-5(R)-hydroxy-1-cyclohexene-1-carboxylate

: 175546-00-6,213027-95-3
3(R),4(R)-epoxy-5(R)-hydroxy-1-cyclohexene-1-carboxylic acid

: 3(S)-chloro-4(S),5(R)-dihydroxy-1-cyclohexene-1-carboxylic acid

Guidance literature:: With hydrogenchloride; at 60 - 70 ℃; for 8h;
DOI:10.1016/0040-4020(96)00574-1

Reference yield:

: 78844-86-7
methyl 3(R),4(R)-epoxy-5(R)-hydroxy-1-cyclohexene-1-carboxylate

: 171963-37-4
3(S),4(S),5(R)-trihydroxy-1-cyclohexene-1-carboxylic acid

: 175546-00-6,213027-95-3
3(R),4(R)-epoxy-5(R)-hydroxy-1-cyclohexene-1-carboxylic acid

Guidance literature:: With sodium hydroxide; In water; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1016/0960-894X(96)00215-6

Reference yield:

: 1199940-76-5
(+)-2-chloroethyl (1R,5R,6S)-5-hydroxy-7-oxabicyclo[4.1.0]hept-2-ene-3-carboxylate

: 175546-00-6,213027-95-3
3(R),4(R)-epoxy-5(R)-hydroxy-1-cyclohexene-1-carboxylic acid

Guidance literature:: (+)-2-chloroethyl (1R,5R,6S)-5-hydroxy-7-oxabicyclo[4.1.0]hept-2-ene-3-carboxylate; With water; potassium hydroxide; In tetrahydrofuran; at 50 ℃;

With hydrogenchloride; In tetrahydrofuran; water; pH=3;
DOI:10.1016/j.tetasy.2009.07.049