1,2-di-O-acetyl-3-O-(3',4'-di-O-acetyl-2',6'-di-O-benzyl-α-D-glucopyranosyl)-5-O-benzyl-α/β-D-ribofuranoside

Base Information

Chemical Name:1,2-di-O-acetyl-3-O-(3',4'-di-O-acetyl-2',6'-di-O-benzyl-α-D-glucopyranosyl)-5-O-benzyl-α/β-D-ribofuranoside
CAS No.:197644-83-0
Molecular Formula:C₄₀H₄₆O₁₄
Molecular Weight:750.797
Hs Code.:

Synonyms:1,2-di-O-acetyl-3-O-(3',4'-di-O-acetyl-2',6'-di-O-benzyl-α-D-glucopyranosyl)-5-O-benzyl-α/β-D-ribofuranoside

Suppliers and Price of 1,2-di-O-acetyl-3-O-(3',4'-di-O-acetyl-2',6'-di-O-benzyl-α-D-glucopyranosyl)-5-O-benzyl-α/β-D-ribofuranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,2-di-O-acetyl-3-O-(3',4'-di-O-acetyl-2',6'-di-O-benzyl-α-D-glucopyranosyl)-5-O-benzyl-α/β-D-ribofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,2-di-O-acetyl-3-O-(3',4'-di-O-acetyl-2',6'-di-O-benzyl-α-D-glucopyranosyl)-5-O-benzyl-α/β-D-ribofuranoside

There total 25 articles about 1,2-di-O-acetyl-3-O-(3',4'-di-O-acetyl-2',6'-di-O-benzyl-α-D-glucopyranosyl)-5-O-benzyl-α/β-D-ribofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 108-24-7
acetic anhydride

: 264230-05-9
3-O-(3',4'-di-O-acetyl-2',6'-di-O-benzyl-α-D-glucopyranosyl)-5-O-benzyl-1,2-O-isopropylidene-α-D-ribofuranoside

: 197644-83-0
1,2-di-O-acetyl-3-O-(3',4'-di-O-acetyl-2',6'-di-O-benzyl-α-D-glucopyranosyl)-5-O-benzyl-α/β-D-ribofuranoside

Guidance literature:: With H₂SO₄-silica; In dichloromethane; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1039/c5ob00440c

Reference yield: 82.0%

: 108-24-7
acetic anhydride

: 3',4'-di-O-acetyl-2',5,6'-tri-O-benzyl-3-O-α-D-glucopyranosyl-D-ribofuranose

: 197644-83-0
1,2-di-O-acetyl-3-O-(3',4'-di-O-acetyl-2',6'-di-O-benzyl-α-D-glucopyranosyl)-5-O-benzyl-α/β-D-ribofuranoside

Guidance literature:: With pyridine; at 20 ℃; for 20h;
DOI:10.1039/a909347h

Reference yield:

: 1125-88-8
benzaldehyde dimethyl acetal

: 197644-83-0
1,2-di-O-acetyl-3-O-(3',4'-di-O-acetyl-2',6'-di-O-benzyl-α-D-glucopyranosyl)-5-O-benzyl-α/β-D-ribofuranoside

Guidance literature:: Multi-step reaction with 7 steps

1: 89 percent / TsOH / dimethylformamide; methanol / 2 h / 70 °C

2: 68 percent / NaCNBH₃; HCl; 3 Angstroem molecular sieves / tetrahydrofuran; diethyl ether / 0.08 h / 20 °C

3: DMSO; Ac₂O / 18 h / 20 °C

4: NaBH₄ / ethanol; H₂O / 1 h / 20 °C

5: 81 percent / ZnCl₂; AgClO₄; 4 Angstroem molecular sieves / dioxane; toluene / 22 h / 20 °C

6: 75 percent / acetic acid; water / ethane-1,2-diol / 0.25 h / Heating

7: 82 percent / pyridine / 20 h / 20 °C

With pyridine; hydrogenchloride; sodium tetrahydroborate; 3 A molecular sieve; 4 A molecular sieve; water; silver perchlorate; acetic anhydride; sodium cyanoborohydride; acetic acid; dimethyl sulfoxide; zinc(II) chloride; toluene-4-sulfonic acid; In tetrahydrofuran; 1,4-dioxane; methanol; diethyl ether; ethanol; water; ethylene glycol; N,N-dimethyl-formamide; toluene; 1: Etherification / 2: Ring cleavage / 3: Oxidation / 4: Reduction / 5: Condensation / 6: Ring cleavage / 7: Acetylation;
DOI:10.1039/a909347h