benzyl 2,5-anhydro-3,4,6-tri-O-p-toluoyl-D-allonothioimidate hydrochloride

Base Information

• Chemical Name: benzyl 2,5-anhydro-3,4,6-tri-O-p-toluoyl-D-allonothioimidate hydrochloride
• CAS No.: 108967-16-4
• Molecular Formula: C₃₇H₃₅NO₇S*ClH
• Molecular Weight: 674.214
• Mol file: 108967-16-4.mol

Synonyms:benzyl 2,5-anhydro-3,4,6-tri-O-p-toluoyl-D-allonothioimidate hydrochloride

Chemical Property of benzyl 2,5-anhydro-3,4,6-tri-O-p-toluoyl-D-allonothioimidate hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 2,5-anhydro-3,4,6-tri-O-p-toluoyl-D-allonothioimidate hydrochloride

There total 1 articles about benzyl 2,5-anhydro-3,4,6-tri-O-p-toluoyl-D-allonothioimidate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2,5-anhydro-3,4,6-tri-O-p-toluoyl-D-allononitrile (86042-36-6) + phenylmethanethiol (100-53-8) → benzyl 2,5-anhydro-3,4,6-tri-O-p-toluoyl-D-allonothioimidate hydrochloride (108967-16-4)

Guidance literature:

With hydrogenchloride; In diethyl ether; at 0 ℃;

DOI:10.1016/S0008-6215(00)90269-6

Reference yield: 77.0%

5,6-diamino-1,3-dimethyluracil monotosylate hydrate + benzyl 2,5-anhydro-3,4,6-tri-O-p-toluoyl-D-allonothioimidate hydrochloride (108967-16-4) → N1-(6-amino-1,3-dimethyluracil-5-yl)-5-O-(p-toluyloxymethyl)-2-furamidine hydrochloride (108967-24-4)

Guidance literature:

In pyridine; for 0.0833333h; Heating;

DOI:10.1016/S0008-6215(00)90269-6

Reference yield:

benzyl 2,5-anhydro-3,4,6-tri-O-p-toluoyl-D-allonothioimidate hydrochloride (108967-16-4) → 1,3-dimethyl-8-<5-O-(p-toluyloxymethyl)-2-furyl>xanthine (108967-25-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / pyridine / 0.08 h / Heating

2: ZnCl₂ / 0.33 h / 180 °C

With zinc(II) chloride; In pyridine;

DOI:10.1016/S0008-6215(00)90269-6

upstream raw materials:

2,5-anhydro-3,4,6-tri-O-p-toluoyl-D-allononitrile

phenylmethanethiol

Downstream raw materials:

N¹-(6-amino-1,3-dimethyluracil-5-yl)-5-O-(p-toluyloxymethyl)-2-furamidine hydrochloride

1,3-dimethyl-8-<5-O-(p-toluyloxymethyl)-2-furyl>xanthine