2-benzenesulfonyl-hexanoic acid ethylamide

Base Information

• Chemical Name: 2-benzenesulfonyl-hexanoic acid ethylamide
• CAS No.: 433977-93-6
• Molecular Formula: C₁₄H₂₁NO₃S
• Molecular Weight: 283.392
• Mol file: 433977-93-6.mol

Synonyms:2-benzenesulfonyl-hexanoic acid ethylamide

Chemical Property of 2-benzenesulfonyl-hexanoic acid ethylamide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-benzenesulfonyl-hexanoic acid ethylamide

There total 2 articles about 2-benzenesulfonyl-hexanoic acid ethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1-iodo-butane (542-69-8) + 2-Benzenesulfonyl-N-ethyl-acetamide (91819-06-6) → 2-benzenesulfonyl-hexanoic acid ethylamide (433977-93-6)

Guidance literature:

2-Benzenesulfonyl-N-ethyl-acetamide; With potassium carbonate; In N,N-dimethyl-formamide;

1-iodo-butane; In N,N-dimethyl-formamide; Further stages.;

DOI:10.1021/ol020062p

Reference yield:

C13H21NO3SSi → 2-benzenesulfonyl-hexanoic acid ethylamide (433977-93-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Acid hydrolysis

2.1: potassium carbonate / dimethylformamide

2.2: 70 percent / dimethylformamide

With potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1021/ol020062p

Reference yield: 93.0%

2-benzenesulfonyl-hexanoic acid ethylamide (433977-93-6) → N-ethylhexanamide (13092-79-0)

Guidance literature:

With disodium hydrogenphosphate; sodium amalgam; In methanol; at 20 ℃; for 2h;

DOI:10.1021/ol020062p

upstream raw materials:

1-iodo-butane

2-Benzenesulfonyl-N-ethyl-acetamide

Downstream raw materials:

N-ethylhexanamide

Refernces