Technology Process of 1-hexyl-7-methylene-5-tosyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine
There total 5 articles about 1-hexyl-7-methylene-5-tosyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dichloro bis(acetonitrile) palladium(II); triphenylphosphine; cesium pivalate;
In
acetonitrile;
at 100 ℃;
for 6h;
Inert atmosphere;
DOI:10.1039/c1cc16110e
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / acetonitrile / 17 h / Reflux
2: copper(l) iodide; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine / tetrahydrofuran / 72 h / 20 °C
3: dichloro bis(acetonitrile) palladium(II); triphenylphosphine; cesium pivalate / acetonitrile / 6 h / 100 °C / Inert atmosphere
With
dichloro bis(acetonitrile) palladium(II); copper(l) iodide; potassium carbonate; triphenylphosphine; cesium pivalate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine;
In
tetrahydrofuran; acetonitrile;
3: Heck reaction;
DOI:10.1039/c1cc16110e
- Guidance literature:
-
Multi-step reaction with 2 steps
1: copper(l) iodide; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine / tetrahydrofuran / 72 h / 20 °C
2: dichloro bis(acetonitrile) palladium(II); triphenylphosphine; cesium pivalate / acetonitrile / 6 h / 100 °C / Inert atmosphere
With
dichloro bis(acetonitrile) palladium(II); copper(l) iodide; triphenylphosphine; cesium pivalate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine;
In
tetrahydrofuran; acetonitrile;
2: Heck reaction;
DOI:10.1039/c1cc16110e
