tert-butyl (1R,2R)-[5-(tert-butyldimethylsilyloxy)-2-hydroxy-1-[4-(methoxymethoxy)benzyl]pentyl]methylcarbamate

Base Information

• Chemical Name: tert-butyl (1R,2R)-[5-(tert-butyldimethylsilyloxy)-2-hydroxy-1-[4-(methoxymethoxy)benzyl]pentyl]methylcarbamate
• CAS No.: 1159215-41-4
• Molecular Formula: C₂₆H₄₇NO₆Si
• Molecular Weight: 497.748

Synonyms:tert-butyl (1R,2R)-[5-(tert-butyldimethylsilyloxy)-2-hydroxy-1-[4-(methoxymethoxy)benzyl]pentyl]methylcarbamate

Chemical Property of tert-butyl (1R,2R)-[5-(tert-butyldimethylsilyloxy)-2-hydroxy-1-[4-(methoxymethoxy)benzyl]pentyl]methylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl (1R,2R)-[5-(tert-butyldimethylsilyloxy)-2-hydroxy-1-[4-(methoxymethoxy)benzyl]pentyl]methylcarbamate

There total 1 articles about tert-butyl (1R,2R)-[5-(tert-butyldimethylsilyloxy)-2-hydroxy-1-[4-(methoxymethoxy)benzyl]pentyl]methylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

tert-butyl (R)-[5-(tert-butyldimethylsilyloxy)-1-[4-(methoxymethoxy)benzyl]-2-oxopentyl]methylcarbamate (1159215-36-7) → tert-butyl (1R,2R)-[5-(tert-butyldimethylsilyloxy)-2-hydroxy-1-[4-(methoxymethoxy)benzyl]pentyl]methylcarbamate (1159215-41-4)

Guidance literature:

With sodium tetrahydroborate; In methanol; ethanol; at -20 ℃; for 3h;

DOI:10.1016/j.tet.2009.03.003

Reference yield: 83.0%

tert-butyl (1R,2R)-[5-(tert-butyldimethylsilyloxy)-2-hydroxy-1-[4-(methoxymethoxy)benzyl]pentyl]methylcarbamate (1159215-41-4) + t-butyldimethylsiyl triflate (69739-34-0) → tert-butyl (1R,2R)-[2,5-bis(tert-butyldimethylsilyloxy)-1-[4-(methoxymethoxy)benzyl]pentyl]methylcarbamate (1159215-45-8)

Guidance literature:

With 2,6-dimethylpyridine; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/j.tet.2009.03.003

Reference yield: 76.0%

tert-butyl (1R,2R)-[5-(tert-butyldimethylsilyloxy)-2-hydroxy-1-[4-(methoxymethoxy)benzyl]pentyl]methylcarbamate (1159215-41-4) → (4R,5R)-5-[3-(tert-butyldimethylsilyloxy)propyl]-4-[4-(methoxymethoxy)benzyl]-3-methyl-1,3-oxazolidin-2-one (1159215-76-5)

Guidance literature:

With sodium hydride; In tetrahydrofuran; for 16h; Reflux;

DOI:10.1016/j.tet.2009.03.003

upstream raw materials:

tert-butyl (R)-[5-(tert-butyldimethylsilyloxy)-1-[4-(methoxymethoxy)benzyl]-2-oxopentyl]methylcarbamate

Downstream raw materials:

(4R,5R)-5-[3-(tert-butyldimethylsilyloxy)propyl]-4-[4-(methoxymethoxy)benzyl]-3-methyl-1,3-oxazolidin-2-one

tert-butyl (1R,2R)-[2,5-bis(tert-butyldimethylsilyloxy)-1-[4-(methoxymethoxy)benzyl]pentyl]methylcarbamate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1159215-41-4 tert-butyl (1R,2R)-[5-(tert-butyldimethylsilyloxy)-2-hydroxy-1-[4-(methoxymethoxy)benzyl]pentyl]methylcarbamate

Send

Send

Metric Ton KG G Pound L ML

Send

Send