3-Amino-6-fluoropyridine-2-carboxamide

Base Information

Chemical Name:3-Amino-6-fluoropyridine-2-carboxamide
CAS No.:175358-03-9
Molecular Formula:C₆H₆FN₃O
Molecular Weight:155.132
Hs Code.:
DSSTox Substance ID:DTXSID101276596
Mol file:175358-03-9.mol

Synonyms:3-amino-6-fluoropyridine-2-carboxamide;175358-03-9;2-Pyridinecarboxamide,3-amino-6-fluoro-(9CI);3-Amino-6-fluoropicolinamide;SCHEMBL6833172;UKGNXGFDUODPGZ-UHFFFAOYSA-N;DTXSID101276596;2-Pyridinecarboxamide, 3-amino-6-fluoro-

Suppliers and Price of 3-Amino-6-fluoropyridine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
3-Amino-6-fluoropicolinamide
1g
$ 3155.55

Alichem
3-Amino-6-fluoropicolinamide
500mg
$ 1853.50

Total 2 raw suppliers

Chemical Property of 3-Amino-6-fluoropyridine-2-carboxamide

Chemical Property:

PSA：82.00000
LogP:1.18330
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:155.04948999
Heavy Atom Count:11
Complexity:164

Purity/Quality:

99%+ ^*data from raw suppliers

3-Amino-6-fluoropicolinamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC(=C1N)C(=O)N)F

Technology Process of 3-Amino-6-fluoropyridine-2-carboxamide

There total 3 articles about 3-Amino-6-fluoropyridine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 171178-31-7
6-fluoro-3-nitropyridine-2-carboxamide

: 175358-03-9
3-amino-6-fluoropyridine-2-carboxamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; for 2h; under 3102.9 Torr;
DOI:10.1021/jm9508651

Reference yield:

: 93683-65-9
6-chloro-3-nitropicolinonitrile

: 175358-03-9
3-amino-6-fluoropyridine-2-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / KF / acetonitrile / 18 h / Heating

2: 61 percent / 90percent H₂SO₄ / 1.5 h / 70 °C

3: H₂ / 5percent Pd/C / ethyl acetate / 2 h / 3102.9 Torr

With potassium fluoride; sulfuric acid; hydrogen; palladium on activated charcoal; In ethyl acetate; acetonitrile;
DOI:10.1021/jm9508651

Reference yield:

: 171178-30-6
2-cyano-6-fluoro-3-nitropyridine

: 175358-03-9
3-amino-6-fluoropyridine-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / 90percent H₂SO₄ / 1.5 h / 70 °C

2: H₂ / 5percent Pd/C / ethyl acetate / 2 h / 3102.9 Torr

With sulfuric acid; hydrogen; palladium on activated charcoal; In ethyl acetate;
DOI:10.1021/jm9508651