(+/-)-4-(4-fluorobenzyl)-2-morpholinylmethanol

Base Information

Chemical Name:(+/-)-4-(4-fluorobenzyl)-2-morpholinylmethanol
CAS No.:156816-54-5
Molecular Formula:C₁₂H₁₆FNO₂
Molecular Weight:225.263
Hs Code.:

Synonyms:(+/-)-4-(4-fluorobenzyl)-2-morpholinylmethanol

Suppliers and Price of (+/-)-4-(4-fluorobenzyl)-2-morpholinylmethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
(4-(4-fluorobenzyl)morpholin-2-yl)methanol 95%
500mg
$ 518.00

Total 2 raw suppliers

Chemical Property of (+/-)-4-(4-fluorobenzyl)-2-morpholinylmethanol

Chemical Property:

Purity/Quality:

99.3% ^*data from raw suppliers

(4-(4-fluorobenzyl)morpholin-2-yl)methanol 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+/-)-4-(4-fluorobenzyl)-2-morpholinylmethanol

There total 4 articles about (+/-)-4-(4-fluorobenzyl)-2-morpholinylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 156925-17-6
(+/-)-2-(chloromethyl)-4-(4-fluorobenzyl)morpholine

: 156816-54-5
(+/-)-4-(4-fluorobenzyl)-2-morpholinylmethanol

Guidance literature:: With water; formamide; for 6h; Heating;
DOI:10.1248/cpb.42.877

Reference yield:

: 22116-33-2
2-(4-fluoro-benzyl-amino)-ethanol

: 156816-54-5
(+/-)-4-(4-fluorobenzyl)-2-morpholinylmethanol

Guidance literature:: Multi-step reaction with 3 steps

1: 4 h / Ambient temperature

2: conc. H₂SO₄ / 0.5 h / 150 °C

3: 96 percent / H₂O, formamide / 6 h / Heating

With sulfuric acid; water; formamide;
DOI:10.1248/cpb.42.877

Reference yield:

: 459-57-4
4-fluorobenzaldehyde

: 156816-54-5
(+/-)-4-(4-fluorobenzyl)-2-morpholinylmethanol

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) NaHCO₃, 2.) NaBH₄ / 1.) MeOH, reflux, 4 h, 2.) a) MeOH, 10 deg C, 0.5 h, b) RT, 2 h

2: 4 h / Ambient temperature

3: conc. H₂SO₄ / 0.5 h / 150 °C

4: 96 percent / H₂O, formamide / 6 h / Heating

With sodium tetrahydroborate; sulfuric acid; water; sodium hydrogencarbonate; formamide;
DOI:10.1248/cpb.42.877