Technology Process of C37H50N4O6
There total 13 articles about C37H50N4O6 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 3h;
DOI:10.1021/ml500137b
- Guidance literature:
-
Multi-step reaction with 7 steps
1: sodium hydrogencarbonate / water; tetrahydrofuran / 20 °C / Large scale
2: potassium carbonate / water; methanol / 96 h / Reflux
3: acetic anhydride / 4.5 h / Reflux
4: hydroquinine (anthraquinone-1,4-diyl) diether / tetrahydrofuran; diethyl ether / -78 - 20 °C
5: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-7-aza-benzotriazole / N,N-dimethyl-formamide / 20 h / 20 °C
6: lithium hydroxide monohydrate / water; tetrahydrofuran / 3 h / 0 - 20 °C
7: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-7-aza-benzotriazole / N,N-dimethyl-formamide / 3 h / 20 °C
With
1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; sodium hydrogencarbonate; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; hydroquinine (anthraquinone-1,4-diyl) diether;
In
tetrahydrofuran; methanol; diethyl ether; water; acetic anhydride; N,N-dimethyl-formamide;
DOI:10.1021/ml500137b
- Guidance literature:
-
Multi-step reaction with 8 steps
1: acetic acid; platinum(IV) oxide; hydrogen / 27 h / 24 °C / 3750.38 Torr / Autoclave; Large scale
2: sodium hydrogencarbonate / water; tetrahydrofuran / 20 °C / Large scale
3: potassium carbonate / water; methanol / 96 h / Reflux
4: acetic anhydride / 4.5 h / Reflux
5: hydroquinine (anthraquinone-1,4-diyl) diether / tetrahydrofuran; diethyl ether / -78 - 20 °C
6: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-7-aza-benzotriazole / N,N-dimethyl-formamide / 20 h / 20 °C
7: lithium hydroxide monohydrate / water; tetrahydrofuran / 3 h / 0 - 20 °C
8: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-7-aza-benzotriazole / N,N-dimethyl-formamide / 3 h / 20 °C
With
platinum(IV) oxide; 1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; hydrogen; sodium hydrogencarbonate; potassium carbonate; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; hydroquinine (anthraquinone-1,4-diyl) diether;
In
tetrahydrofuran; methanol; diethyl ether; water; acetic anhydride; N,N-dimethyl-formamide;
DOI:10.1021/ml500137b