4,4,10,14-Tetramethyl-17-(6-methylhept-5-en-2-yl)-1,2,3,5,6,7,11,12,13,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol

Base Information

Chemical Name:4,4,10,14-Tetramethyl-17-(6-methylhept-5-en-2-yl)-1,2,3,5,6,7,11,12,13,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol
CAS No.:175205-40-0
Molecular Formula:C₂₉H₄₈O
Molecular Weight:412.7
Hs Code.:
DSSTox Substance ID:DTXSID70372281
Mol file:175205-40-0.mol

Synonyms:175205-40-0;4,4,10,14-tetramethyl-17-(6-methylhept-5-en-2-yl)-1,2,3,5,6,7,11,12,13,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol;17-(1,5-dimethylhex-4-enyl)-4,4,10,14-tetramethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol;18-Nordammara-8,24-dien-3-ol;DTXSID70372281;17-(1,5-Dimethylhex-4-enyl)-4,4,10,14-tetramethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phe;FT-0607255;4,4,14-Trimethyl-18-norcholesta-8,24-dien-3-ol;(1S,2S)-N,N,N,N-TETRAMETHYL-1,2-DIPHENYLETHANE-1,2-DIAMINE;3a,6,6,9a-tetramethyl-1-(6-methylhept-5-en-2-yl)-1H,2H,3H,3aH,4H,5H,5aH,6H,7H,8H,9H,9aH,10H,11H,11aH-cyclopenta[a]phenanthren-7-ol

Suppliers and Price of 4,4,10,14-Tetramethyl-17-(6-methylhept-5-en-2-yl)-1,2,3,5,6,7,11,12,13,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
17-(1,5-DIMETHYLHEX-4-ENYL)-4,4,10,14-TETRAMETHYL-2,3,4,5,6,7,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-OL 95.00%
5MG
$ 504.88

Total 4 raw suppliers

Chemical Property of 4,4,10,14-Tetramethyl-17-(6-methylhept-5-en-2-yl)-1,2,3,5,6,7,11,12,13,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol

Chemical Property:

Vapor Pressure:7.07E-12mmHg at 25°C
Refractive Index:1.531
Boiling Point:495.1°Cat760mmHg
Flash Point:217.7°C
PSA：20.23000
Density:0.99g/cm³
LogP:8.08900
XLogP3:8.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:412.370516150
Heavy Atom Count:30
Complexity:723

Purity/Quality:

98%Min ^*data from raw suppliers

17-(1,5-DIMETHYLHEX-4-ENYL)-4,4,10,14-TETRAMETHYL-2,3,4,5,6,7,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-OL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CCC=C(C)C)C1CCC2(C1CCC3=C2CCC4C3(CCC(C4(C)C)O)C)C

Technology Process of 4,4,10,14-Tetramethyl-17-(6-methylhept-5-en-2-yl)-1,2,3,5,6,7,11,12,13,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol

There total 8 articles about 4,4,10,14-Tetramethyl-17-(6-methylhept-5-en-2-yl)-1,2,3,5,6,7,11,12,13,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 19902-79-5
28-noroxidosqualene

: 175205-40-0
18-norlanosterol

Guidance literature:: 28-noroxidosqualene; With hog liver cyclase; at 37 ℃; for 12h; Inert atmosphere; Enzymatic reaction;

With potassium hydroxide; In methanol; at 70 ℃; for 0.5h; Inert atmosphere;
DOI:10.1002/chem.201201779

Reference yield:

: (S)-2,2-Dimethyl-3-((3E,7E,11E,15E)-3,7,16,20-tetramethyl-henicosa-3,7,11,15,19-pentaenyl)-oxirane

: 175205-40-0
18-norlanosterol

Guidance literature:: (cyclization);
DOI:10.1021/ja01014a081

Reference yield:

: 1417697-31-4
(2E,6E,10E)-14-bromo-7,11,15-trimethylhexadeca-2,6,10-triene-1,15-diol

: 175205-40-0
18-norlanosterol

Guidance literature:: Multi-step reaction with 4 steps

1.1: phosphorus tribromide / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

2.1: N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -30 °C / Inert atmosphere

2.2: 1 h / -78 °C / Inert atmosphere

3.1: dichloro [1,1'-bis(diphenylphosphino)propane]palladium(II); lithium triethylborohydride / diethyl ether; tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

4.1: hog liver cyclase / 12 h / 37 °C / Inert atmosphere; Enzymatic reaction

4.2: 0.5 h / 70 °C / Inert atmosphere

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; dichloro [1,1'-bis(diphenylphosphino)propane]palladium(II); hog liver cyclase; phosphorus tribromide; lithium triethylborohydride; In tetrahydrofuran; diethyl ether; hexane;
DOI:10.1002/chem.201201779