2-amino-1-benzyl-4-methylthio-6-oxo-N-phenyl-5-cyano-1,6-dihydropyridin-3-ylcarboxamide

Base Information

• Chemical Name: 2-amino-1-benzyl-4-methylthio-6-oxo-N-phenyl-5-cyano-1,6-dihydropyridin-3-ylcarboxamide
• CAS No.: 1373943-78-2
• Molecular Formula: C₂₁H₁₈N₄O₂S
• Molecular Weight: 390.466
• Mol file: 1373943-78-2.mol

Synonyms:2-amino-1-benzyl-4-methylthio-6-oxo-N-phenyl-5-cyano-1,6-dihydropyridin-3-ylcarboxamide

Chemical Property of 2-amino-1-benzyl-4-methylthio-6-oxo-N-phenyl-5-cyano-1,6-dihydropyridin-3-ylcarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-amino-1-benzyl-4-methylthio-6-oxo-N-phenyl-5-cyano-1,6-dihydropyridin-3-ylcarboxamide

There total 1 articles about 2-amino-1-benzyl-4-methylthio-6-oxo-N-phenyl-5-cyano-1,6-dihydropyridin-3-ylcarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

N-Benzylcyanoacetamide (10412-93-8) + 2-cyano-3,3-bis(methylthio)-N-phenylacrylamide (17917-51-0) → 2-amino-1-benzyl-4-methylthio-6-oxo-N-phenyl-5-cyano-1,6-dihydropyridin-3-ylcarboxamide (1373943-78-2)

Guidance literature:

N-Benzylcyanoacetamide; With potassium hydroxide; In dimethyl sulfoxide; for 0.25h;

3,3-bis(methylthio)-2-cyano-N-phenylacrylamide; In dimethyl sulfoxide; at 80 ℃; regiospecific reaction;

DOI:10.1134/S1070363212030164

upstream raw materials:

N-Benzylcyanoacetamide

2-cyano-3,3-bis(methylthio)-N-phenylacrylamide